2022 AFC South Betting Odds: Colts Are Favored, Jaguars Could Compete

GamingToday.com is an independent sports news and information service. GamingToday.com has partnerships with some of the top legal and licensed sportsbook companies in the US. When you claim a bonus offer or promotion through a link on this site, Gaming Today may receive referral compensation from the sportsbook company. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

For more information, please read How We Rank Sportsbooks, Privacy Policy, or Contact Us with any concerns you may have.

Gaming Today is licensed and regulated to operate in AZ, CO, CT, IN, KS, LA, MI, NJ, NY, PA, TN, and VA.

AFC South futures odds are up and ready for betting at sportsbooks, and the Indianapolis Colts, led by the NFL’s top running back in Jonathan Taylor, are consensus favorites to win the division. The Tennessee Titans check in as the second betting choice as they seek their third straight AFC South title.

The Jacksonville Jaguars and Houston Texans round out the top-heavy division and both teams are expected to finish in the back of the pack. The Jags, however, could see some improvement in QB Trevor Lawrence’s second season as a pro.

Bet NFL futures here: Code TODAY15 Gets $1,500 Risk-Free Bet at Caesars

Odds to Win the AFC South

Here are AFC South futures odds across the sports betting industry, current as of Monday, Aug. 22.

AFC South OddsDraftKingsCaesars (Code TODAY15)BetMGM (Code TODAY)FanDuel
Indianapolis Colts-130 -125 -140 -125
Tennessee Titans+175+170+180+170
Jacksonville Jaguars+750+650+800+750
Houston Texans+3000+3500+3000+2500

Bet NFL Futures here: Get $1,000 ‘No Sweat First Bet’ at FanDuel

Indianapolis Colts

Matt Ryan takes over as Indy’s starting QB, and at 37 years old, you wonder if his best years are behind him. This is the age of aging QBs, though, as Tom Brady (soon to be 45) and Aaron Rodgers (38) are still playing at an elite level.

The Colts will again rely on the run with Taylor leading the attack. Taylor led the NFL with 1,811 rushing yards and 18 TDs last season. He also ranked second on the team with 40 catches out of the backfield.

Colts RB Jonathan Taylor (Photo by Ken Murray/Icon Sportswire)
RB Jonathan Taylor and the Indianapolis Colts are favored in the 2022 AFC South Betting Odds. (Photo by Ken Murray/Icon Sportswire)

There appears to be some urgency in Indy for the Colts to win their first division title since 2014. The Colts added pass-rush specialist Yannick Ngakoue and shutdown CB Stephon Gilmore to their defense. Pro Football Focus ranked Indy’s D-Line at No. 11 in the NFL heading into the 2022-23 season.

The Colts also have the schedule working in their favor. Indy has the 27th easiest schedule in the NFL, and it includes a total of four games against division weaklings in the Texans and Jaguars.

But lest we forget, it was Jacksonville that put a dagger in Indy’s playoff hopes with a 26-11 win in the final week of the regular season last year.

Bet NFL at PointsBetClaim two risk-free bets worth $2,000 with code ‘BONUSDAY’

Tennessee Titans

The big news out of Tennessee recently had WR Julio Jones being released. In one of the more surprising moves of the offseason, Tennessee previously traded top WR AJ Brown to the Philadelphia Eagles. That leaves the Titans a tad thin when it comes to pass catchers, but they did acquire Robert Woods from the LA Rams, and expectations are high for first-round pick Treylon Burks.

Derrick Henry will continue to be the lynchpin on offense after his return from a foot injury. Henry is the betting favorite to become the NFL’s Comeback Player of the Year. Henry was limited to eight games last season and still managed to amass 937 rushing yards and 10 TDs.

Tennessee returns a majority of starters on defense. The Titans led the league in rushing defense last season and ranked fourth in points allowed per game (19). DE Jeffery Simmons, who had 11.5 sacks a year ago, is one of the NFL’s elite pass-rushing specialists.

Bet NFL futures hereClaim a $50 Free Bet & $1,000 Bonus at DraftKings

Jacksonville Jaguars

Jacksonville’s Urban Meyer experiment was a disaster, but there is some hope for the Jags heading into the new season. RB Travis Etienne said he has completely recovered from the Lisfranc injury that sidelined him for all of his rookie season.

Etienne and QB Trevor Lawrence were college teammates at Clemson. Pro Football Focus pegged Lawrence as its top candidate to have a breakout season.

That bodes well for the Jags, who haven’t had a winning season since 2017 when they went 10-6. Jacksonville finished last season with the worst record in the NFL at 3-14.

No. 1 NFL draft pick and former Georgia DE Travon Walker is among the newcomers on Jacksonville’s defense, which should be much improved this season. Other key additions include Darious Williams, Foyesade Oluokun, Folorunso Fatukasi, and Devin Lloyd. Lloyd, a linebacker from Utah, was also selected in the first round at No. 27.

We’re not brazen enough to pick the Jags to win the AFC South this season, but take a look at their season win totals at sportsbooks. FanDuel is offering +115 odds on Jacksonville going Over 6.5 wins. With Super Bowl-winning coach Doug Pederson now in charge — and Meyer long gone — that’s a bet worth making on a team that could be the most improved in the NFL this season.

Houston Texans

Lovie Smith takes over as head coach for Houston, but there’s little to love about the Texans heading into this season. While optimism abounds during training camp, and fans believe their team can make the playoffs and even win the Super Bowl, only the most delusional Texans fans can make those claims.

Davis Mills is now Houston’s starting QB. The former Stanford Cardinal has a career record of 2-9, but that’s probably not all his fault. The Texans were terrible, for lack of a better word, last season.

Don’t expect things to get much better this fall. Houston is in its second straight “rebuilding” season. The Texans have the longest odds of all NFL teams to win Super Bowl 57. DraftKings and PointsBet were both dealing Houston at +25000 odds as of Thursday, Aug. 18.

Also read: NFC Odds 2022: Fade the Bucs | What is Your NFL Team’s Chance of Making the Playoffs? | 2022 NFL Season Win Totals

Additional NFL Futures Betting Markets

Check out our live Super Bowl 57 odds page. Here are some additional futures markets you might be interested in:

  •  At DraftKings, the Bills and Bucs head into the season with the highest season win totals at 11.5. What teams go Over their season win total during the upcoming NFL season? Be careful with the Dallas Cowboys. DraftKings enticed Dallas backers by putting up 10 wins and -110 on the over. The Cowboys were 12-5 last season, but it had been five years since they last eclipsed 10 wins.
  •  What are your favorite team’s chances of making the NFL playoffs? Check out odds for all 32 teams here.
  • The Bills are favored to win the conference, but the Chiefs and Raiders offer much better value in AFC odds. Las Vegas could be this year’s version of the Cincinnati Bengals.
  •  In the NFC, fade the Bucs and Packers to win the conference this year. The Rams are a better bet to repeat as NFC champions, and the Eagles are worth a wager at juicy odds.

Frequently Asked Questions

Who is favored to win the AFC South?

The Indianapolis Colts are the favorite to win the AFC South at odds of -130 at DraftKings.

Who won the AFC South title last year?

The Tennessee Titans captured their second straight AFC South division title last year.

Who shouldn't I bet on to win the AFC South?

The Houston Texans are a dumpster fire. We wouldn’t bet on them even with your money.

What sportsbook has the best odds on AFC South teams?

No single sportsbook can claim to have the best odds on every team. That’s why you need to compare odds at multiple sportsbooks to find the best odds for your bet.

What AFC South team will be most improved this year?

The Jacksonville Jaguars have a great chance to carry this banner under new head coach Doug Pederson. The Jags were a league-worst 3-14 last season, but we’re bullish on them winning seven games this year.

When was the last time an AFC South team won the Super Bowl?

That came in 2007 when the Colts defeated the Chicago Bears, 29-17.

About the Author
Kris Johnson

Kris Johnson

Writer & Contributor
Kris Johnson is a Senior Writer at Gaming Today with more than 15 years of experience as a sports journalist. Kris' work has appeared in Sports Business Daily, Sports Business Journal, NASCAR Illustrated, and more. Kris also authored a sports betting novel entitled The Endgame.

Get connected with us on Social Media