Two dark horse candidates meet as Benfica hosts Inter Milan in the UEFA Champions League quarterfinals. Here, we look at Benfica vs. Inter Milan odds, props, and a prediction for Tuesday’s first-leg match in Lisbon.
Benfica cruised with a 7-1 aggregate win over Club Brugge in the Round of 16. After taking a 2-0 win on the road, the 37-time Portuguese league champions opened the floodgates for a 5-1 victory at the Estádio da Luz, the site of this encounter.
Inter Milan will face a team from the Primeira Liga after eliminating Benfica’s rival Porto in the previous round. A 1-0 win in Italy was all that was needed to separate the two and now the 19-time Serie A champions hope for another conquest over a team from Portugal.
Benfica vs. Inter Milan Odds: Moneyline & Total
Here are the betting lines from top US sportsbooks for Tuesday’s Champions League match between Benfica and Inter Milan.
These odds reflect the prices for both sides on the three-way line, where a bet on either team is a loss in the event of a draw. DraftKings is offering the best price on Benfica at +120 while BetRivers is offering the best price on Inter at +270. If you’re predicting a draw in this match, both of those sportsbooks have it priced at +235 as of Monday afternoon.
The odds are likely to change as we get closer to kickoff, and it’s always advised to weigh the options at various sports betting apps to find the best sportsbook bonuses and prices.
SOCCER · Tue (4/11) @ 3:00 pm ET
Inter Milan | at | Benfica |
Estádio do Sport Lisboa e Benfica, Lisbon, PT |
Benfica Roster, Injuries, and Betting News

The two-time European champions last won the competition during the 1961-62 season. Advancing to the next round, and reaching the semifinals, would be the farthest the club has gone this millennium.
Benfica are currently first in the Primeira Liga with 71 points, seven points removed from second place Porto, and have a good cushion to fall back on. They can start to put all their marbles on a UEFA Champions League run and make some history.
Roster
Forwards Gonçalo Ramos and João Mário lead the team in goals with 17 each. Ramos is this season’s club leader across all competitions with 25 and will be one of the prime targets to watch.
Mario is one of the leaders of the team alongside captain Nicolás Otamendi. The Argentine is coming off a FIFA World Cup conquest with Argentina and is now looking to see Benfica off to a historic season of their own.
Injuries
Julian Draxler (ankle), Goncalo Guedes (knee), Mihailo Ristic (hamstring), and Nicolas Otamendi (suspension) are all out for this encounter. Alexander Bah (knee) is doubtful.
Inter Milan Roster, Injuries, and Betting News
Italian legend Simone Inzaghi hopes to lead Inter to its first UEFA Champions League title since 2009-10. With a favorable draw in Benfica, Inter could salvage its season with a promising European run.
The season for one of Italy’s biggest clubs has been a disappointment with the current fifth place in the standings. One point behind rivals A.C. Milan, the club is fighting to qualify for next year’s UCL.
Roster
Lautaro Martinez is clearly the man up front for Inter with 14 league goals and 17 across all competitions. Martinez leads both those categories for the club but needs to take the next step in his career to be considered among Europe’s elite strikers.
With Romelu Lukaku and Edin Džeko as depth pieces, Inter could very well have the edge in attack. They’ll look to goalkeeper Samir Handanović, the team captain, to keep goals to a minimum as its forward core works on advancing to the semifinals.
Injuries
Dalbert (knee) is out. Milan Skriniar (back) and Hakan Calhanoglu (groin) are doubtful.
Benfica vs. Inter Milan Props
Below is a sampling of props for Benfica vs. Inter Milan.
Anytime Goalscorer (DraftKings):
- Joao Mario: +185
- Goncalo Ramos: +185
- Lautaro Martinez: +240
- Petar Musa: +250
- Romelu Lukaku: +260
- Casper Tengstedt: +260
- Edin Dzeko: +275
Correct Score (FanDuel):
- Benfica 1-0: +600
- Benfica 2-0: +900
- Benfica 2-1: +800
- Inter 1-0: +950
- Inter 2-0: +1800
- Inter 2-1: +1200
- 0-0: +750
- 1-1: +500
Total Goal Props (DraftKings):
- Over 0.5 goals -1800, Under 0.5 goals: +850
- Over 1.5 goals -270, Under 1.5 goals: +210
- Over 2.5 goals +115, Under 2.5 goals: -145
- Over 3.5 goals +300, Under 3.5 goals: -425
- Over 4.5 goals +700, Under 4.5 goals: -1400
Benfica vs. Inter Milan Broadcast Info: Where to Watch
- Date/Time: Tuesday, Apr. 11, 3 p.m. ET
- Location: Estádio do Sport Lisboa e Benfica
Watch this match at one of the following:
- Paramount+ (English)
- Univision / TUDN / ViX (Spanish)
Benfica vs. Inter Milan Prediction
Benfica could use a healthy home win to have a shot into the next round but keeping a clean sheet would be the biggest win, setting them up well for an away goals advantage. Inter is a tough side to defend, however, especially if they have all their top players available.
Here are a few bets available at DraftKings that are worth checking out:
- Inter (+250)
- Spread: Inter +0.5 (-150)
- Anytime scorer: Ramos (+185), Martinez (+240)
Also read: Premier League futures | 2026 World Cup odds
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