Broncos vs. Chargers Odds & Prediction: LA the Favorite on MNF, But… is an independent sports news and information service. has partnerships with some of the top legal and licensed sportsbook companies in the US. Gaming Today may receive referral compensation from the sportsbook company when you claim a bonus offer or promotion through a link on this site. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

For more information, please read How We Rate Sportsbooks, Privacy Policy, or Contact Us with any concerns you may have.

Gaming Today is licensed and regulated to operate in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, ME, MI, MS, NJ, NV, NY, OH, ON, PA, TN, VA, VT, WV, and WY.

The Denver Broncos play the Los Angeles Chargers on the road to close out Week 6 of the 2022 NFL season.

As of noon on Monday, the Chargers are listed as 4- to 4.5-point favorites on oddsboards for this MNF divisional clash. That’s down from the opening line posted last Sunday night that ranged between -6 and -6.5.  This marks the fifth time this season that LA has been a favorite.

Let’s take a look at our Broncos vs. Chargers odds on Monday Night Football, as well as a prediction.

MNF Odds: Point Spread, Moneyline, Total

Here are Monday Night Football odds from around the sports betting marketplace.

DEN Broncos vs LA Chargers Odds NFL Odds

NFL · Mon (10/17) @ 8:15pm ET

DEN Broncos at LA Chargers
SoFi Stadium, Inglewood, California

Bet Broncos vs. Chargers at DraftKings: Up to $1,250 Bonus

Broncos-Chargers AFC West Battle on MNF

For a league-high fourth time this season, the Broncos (2-3 Straight Up/1-4 Against The Spread) will be playing in prime time (with one more to come), but surely the TV networks were expecting a lot more from QB Russell Wilson and Co. after the blockbuster offseason trade that brought him in from Seattle.

Denver has scored only six offensive TDs this season, which ties for the fewest in the NFL. And making matters worse, Wilson has been playing with a partially torn lat near his throwing shoulder.

But that’s probably not an excuse for him throwing fourth-quarter INTs from the Colts’ 35 and 13 in last Thursday’s 12-9 home loss to Indianapolis. Not to mention the awkward game-ending incompletion into a crowd in the end zone on fourth-and-1 in OT. It was a curious throw and a more curious play call from rookie head coach Nathaniel Hackett.

Denver QB Russell Wilson may pull of an upset in our Broncos vs. Chargers odds & prediction. (AP Photo/David Zalubowski)

The Chargers (3-2 SU/4-1 ATS), meanwhile, also have a QB that has fought through an injury in Justin Herbert, who fractured his rib cartilage in a Week 2 game against Kansas City.

He is the league’s fifth-rated passer with 10 TD throws and only two interceptions. But he’s still going without veteran standout WR Keenan Allen (questionable, hamstring), who has missed the past four games.

A big difference between the teams’ offenses is the running game.

Last week, LA’s Austin Ekeler broke through for 173 ground yards in a 30-28 victory in Cleveland as the Chargers overcame an early 14-0 deficit to win their second game in a row. Entering Week 6, that’s the most yards for anyone in a game this season.

Denver, meanwhile, lost tackle-busting RB Javonte Williams in Week 4 (IR, knee) for an offense that has scored only three TDs on nine first-and-goal possessions. The Broncos still have speedy ex-Charger Melvin Gordon but are wary about his fumble issues (three total, two lost).

Defensively, the Broncos’ third-ranked unit is tied with division leaders San Francisco and Dallas for the fewest touchdowns allowed with five. Last week, Denver didn’t allow any to Indy and still lost.

By contrast, the Chargers have allowed 15 offensive TDs, including four by Cleveland and backup QB Jacoby Brissett last week. Two games earlier, Jacksonville also scored four against them. In the Jags’ other four games, they scored seven.

Bet MNF at BetMGM: Use promo code TODAY for a $1,000 Risk-Free Bet

Broncos vs. Chargers MNF Prediction

In their previous eight meetings with the Chargers dating to 2018, the Broncos have been an underdog each time, but have won five of them.

Could they pull another upset? Or at least make it close? Sure.

Two reasons are that the Chargers have been playing without star pass rusher Joey Bosa (IR, groin). And on offense, LA is going with a backup at left tackle against a team that had six sacks last week against a Colts squad that also was playing with a second-teamer in that spot.

And although the Chargers were certainly proud of their rushing performance in Cleveland, that was against a unit that’s allowed 5.3 yards a carry.

And speaking of crummy run defense, LA is atop the chart at 5.8 a rush.

So, if Gordon can emphasize smothering the ball on carries and if maybe Wilson and WRs Courtland Sutton and Jerry Jeudy can get on the same page a little better than last week, Denver could pull a surprise.

Wilson also should benefit from the extended break after the team’s Thursday night outing.

Prediction: Broncos 20, Chargers 16

Also read: NFL Week 6 betting picks and predictions | NFL Week 6 player props and anytime TD scorer bets

About the Author
Bob Christ

Bob Christ

Bob Christ, based in New Mexico, is a sports betting writer at Gaming Today. He has been a gaming writer (primarily for the NFL) for more than four decades, with his work appearing in publications and websites across North America. Christ is a big fan of the Arkansas Razorbacks, Philadelphia Eagles and Phillies, and the NHL's Winnipeg Jets.

Get connected with us on Social Media