Arizona Cardinals vs. Los Angeles Rams Odds: 2022 NFL Wildcard Game On MNF is an independent sports news and information service. has partnerships with some of the top legal and licensed sportsbook companies in the US. When you claim a bonus offer or promotion through a link on this site, Gaming Today may receive referral compensation from the sportsbook company. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

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Rams QB Matthew Stafford (Photo by Jevone Moore/Icon Sportswire)
ARI Cardinals vs LA Rams Odds NFL Odds

NFL · Mon (1/17) @ 8:17pm ET

ARI Cardinals at LA Rams
SoFi Stadium, Inglewood, California

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The Arizona Cardinals and L.A. Rams will clash at SoFi Stadium on Monday Night Football to close out the NFL Wildcard Playoff round.

The line opened with the Rams -4.5, but it’s now a consensus -4 across the industry at sportsbooks including BetMGM and Caesars Sportsbooks.

Arizona Cardinals (11-6, 10-7 ATS) at LA Rams (12-5, 8-9)

Time: 8:15 p.m. EST

Line: Rams -4 (49)

The skinny: The game will be the first wild-card event played on a Monday since 1988, when Minnesota beat the visiting Rams.

Facts: The teams split their two games this season, with the visitors winning as an underdog both times — Arizona in Week 4, 37-20, amid its 7-0 start — and in Week 14 L.A. prevailed 30-23 during its five-game winning streak.

The Cardinals blew a chance to win the NFC West title last week, losing at home 38-30 to going-nowhere Seattle. Arizona gave up 202 rushing yards to the Seahawks, it’s worst defensive performance of the season.

The Rams, meanwhile, blew a 17-0 lead to San Francisco and lost 27-24 in OT. It was the biggest blown edge in defeat for any home team this season.

Despite the star power at QB for both teams, Arizona’s Kyler Murray has struggled since that dazzling start to the season with the Cardinals going 1-4 down the stretch. L.A.’s Matthew Stafford, meanwhile, is tied for the league lead with 17 INTs this season, including a league-high four pick-sixes.

The Cardinals might not mind playing on the road, where they have a league-best 8-1 mark this season. They were only 3-5 at home in the desert, tied for the worst home record among playoff teams.

Full Sportsbook Odds for Cardinals vs Rams

Bet TypeSpreads

Analysis: Over the past two weeks, the Cardinals have settled too many times for field goals while deep in enemy territory. Three times vs. Seattle’s 28th-ranked defense, drives stalled inside the 25. A week earlier vs. Dallas, Arizona kicked field goals twice after getting inside the 10. And last week’s loss to Seattle was a little harsher than the score might indicate, for the Cardinals scored on a fumble return and another turnover to set up Murray and Co. at the Seahawks 1. It took them only two plays to reach the end zone.

Even in the Cardinals’ 30-23 loss to the Rams four weeks ago, Murray did throw for a Week 14-high 383 yards, but his passer rating was only 72.1, third lowest for any passer with 300-plus yards this year. And, no, star WR DeAndre Hopkins (knee) won’t be returning this week. Maybe next week, or the week after if the Cardinals are still alive.

Arizona’s running game is also the feeling the pain from injuries to RBs Chase Edmonds (ribs) and James Conner (ribs/heel). Both are listed as questionable.

The Rams have an injury concern of their own with Stafford, who injured a toe last week. He didn’t show off that toe to the media like Aaron Rodgers, so no further details.

But anyway, this time the Rams will actually have a home-fan edge after noisy 49ers rooters made it hard for Stafford and his offense to hear signals last week.

Cardinals at Rams Pick

Rams 30, Cardinals 19

Last week: 5-8 ATS, 8-5 SU

Season total: 125-131 (.488) ATS, 159-99-1 (.617) SU

About the Author
Bob Christ

Bob Christ

Bob Christ, based in New Mexico, has been a gaming writer (primarily the NFL) for almost four decades, with his work appearing in publications/websites across North America. He's a big fan of the Arkansas Razorbacks, Philadelphia's Eagles and Phillies, and inexplicably the NHL's Winnipeg Jets.

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