Sunday’s slate of Week 10 games caps off with a clash between two California teams looking to find some rhythm. The Los Angeles Chargers (5-3) take a short flight to face the San Francisco 49ers (4-4) at Levi’s Stadium in primetime.
A lot of stars are set to hit the field in this Sunday Night Football showdown, which makes for a perfect opportunity to wager on player props.
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Los Angeles Chargers vs. San Francisco 49ers Odds
The 49ers – priced between -305 and -357 on the moneyline as of Saturday evening – are favored by 7.5 points against the visiting team. Los Angeles’ odds range from +240 and +275, with longest odds found at Caesars.
Recent betting trends favor Los Angeles, who is 4-0 against the spread (ATS) in road games this season. Meanwhile, the Niners have struggled under HC Kyle Shanahan at Levi’s Stadium, posting a 8-17-1 ATS record in their last 26 games as a home favorite.
Bettors are keeping up with these trends, with the Chargers receiving 60% of the handle at DraftKings.
Bettors can find the Over/Under total for this star-studded contest at either 45 or 45.5 points on legal US sports betting apps.
Also read: Chargers vs. 49ers Odds & Prediction
NFL · Sun (11/13) @ 8:20pm ET
| LA Chargers | at | SF 49ers |
| Levi's Stadium, Santa Clara, California | ||
Player Props, TD Scorer Bets for SNF Week 10
Christian McCaffrey Over 81.5 Rushing Yards (-115, BetMGM)
Christian McCaffrey was born to play under Shanahan, who knows how to utilize running backs better than anyone. In his first start with the Niners, McCaffrey totaled 94 yards rushing against a stout rushing defense in the Los Angeles Rams last week.
Running backs have favored really well against the Chargers this season, including James Robinson (100 yards), Dameon Pierce (131), Nick Chubb (134), Kenneth Walker (167), and even Tyler Allgeier (99).
McCaffrey is poised to induct himself onto that list against a Chargers team that allows the fourth most rushing yards in the NFL (145.5 per game).
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Joshua Palmer Over 51.5 Receiving Yards (-119, Caesars)
With both Keenan Allen and Mike Williams out against the Atlanta Falcons last week, Palmer stepped up and led the Chargers in all receiving categories to the tune of eight catches on 10 targets for 106 yards.
Palmer will be the de facto WR1 against San Francisco, and while he may not have the talent of a true WR1, somebody’s going to have to catch passes in this offense.
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Now, Ekeler – a running back – has the third most catches in the entire NFL this season, so he’s going to be peppered with targets yet again. But that shouldn’t get in the way of Palmer, who has topped his Week 10 receiving prop total in each of his last two outings.
The 49ers have allowed 12 different opposing players to amass 52-plus receiving yards over their last five games, so it’s highly possible that two – or even three – different Chargers players have a good receiving day this Sunday night.
Jimmy Garoppolo Over 2.5 Rushing Yards (-115, DraftKings)
What’s good about immobile quarterbacks is that it normally takes just one rushing attempt to exceed their low rushing prop totals. In the case of Garoppolo, he has topped his Week 10 rushing prop total in four of his seven games this season.
Multiple opposing quarterbacks have had quality days running the ball against Los Angeles this season. Even the sluggardly Jacoby Brissett of the Cleveland Browns turned three carries into 32 yards in Week 5.
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More on NFL betting: NFL Week 10 Teaser Pick | NFL Week 10 Player Props & TD Scorers
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