2023 College Football Week 3 Odds, Picks, Predictions: How to Bet Colorado-Colorado State, Florida-Tennessee

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Week 3 of the college football slate lacks anything quite like last Saturday night’s Alabama-Texas showdown but still features some intriguing matchups like Mississippi State vs. No. 14 LSU and Florida vs. No. 11 Tennessee in the SEC, as well as No. 18 Colorado vs. Colorado State. Colorado will host ESPN College Gameday for Coach Prime’s third game as coach of the Buffaloes. 

We recommend the best college football betting sites in our odds overview for the best games of Week 3. Let’s break down the best College Football Week 3 odds and analyze a few of the best matchups here.

College Football Odds for Week 3

View the table below to find the latest live college football odds. You can search for a specific team to see its odds directly. By clicking on the preferred odds below, you can sign up for the sportsbook and place a wager.

Week 3 College Football Odds for AP Top 25 Teams

The best available odds for home team spreads are listed along with game totals across top sports betting apps.

  • 3 Florida State at Boston College (, )
  • 7 Penn State at Illinois (, )
  • 14 LSU at Mississippi State (, )
  • 15 Kansas State at Missouri (, )
  • Central Michigan at 9 Notre Dame (, )
  • South Carolina at 1 Georgia (, )
  • 10 Alabama at South Florida (, )
  • San Diego State at 16 Oregon State (, )
  • 19 Oklahoma at Tulsa (, )
  • Minnesota at 20 North Carolina (, )
  • Northwestern at 21 Duke (, )
  • Western Michigan at 25 Iowa (, )
  • Western Kentucky at 6 Ohio State (, )
  • 8 Washington at Michigan State (, )
  • 11 Tennessee at Florida(, )
  • Bowling Green at 2 Michigan (, )
  • Georgia Tech at 17 Ole Miss (, )
  • Wyoming at 4 Texas (, )
  • Hawaii at 13 Oregon (, )
  • Colorado State at 18 Colorado (, )

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Colorado State at No. 18 Colorado

The Buffs' offense wasn't quite as dominant against Nebraska as it was against TCU in Week 1, but QB Shedeur Sanders still finished with 393 yards through the air on 31-for-42 passing.
The Buffs’ offense wasn’t quite as dominant against Nebraska but QB Shedeur Sanders still finished with 393 yards. (AP Photo/David Zalubowski)
  • Time: Saturday, 10:00 p.m. ET
  • TV/Live Stream: ESPN

Colorado is at home again this weekend after winning the first game at Folsom Field under Deion Sanders, 36-14, over Nebraska. The Buffs’ offense wasn’t quite as dominant against Nebraska as it was against TCU in Week 1, but QB Shedeur Sanders still finished with 393 yards through the air on 31-for-42 passing. The question for Colorado is whether or not the offensive line play can improve after that unit allowed eight sacks to Nebraska and struggled to open up holes, as the Buffaloes ran for just 58 yards on 33 carries.

Colorado State is 0-1 after losing to Washington State in Week 1, followed by a bye week last Saturday. The Rams were not competitive against Washington State, as they lost 50-24 and allowed WSU QB Cam Ward to throw for over 450 yards. That performance does not bode well for CSU’s chances in Boulder this weekend, but given the rivalry between these teams and the extra week to prepare, Colorado State feels like a solid bet to cover .

Pick: Over .

No. 11 Tennessee at Florida

  • Time: Saturday, 7:00 p.m. ET
  • TV/Live Stream: ESPN

The Volunteers are one of the most intriguing teams in the country after going 11-2 last season and losing QB Hendon Hooker and WRs Jalin Hyatt and Cedric Tillman to the NFL Draft. But with talented 23-year-old Joe Milton stepping in for Hooker to take the helm of Josh Heupel‘s quarterback-friendly system, the Vols should once again be potent offensively. Their Week 2 performance against Austin Peay, however, did not inspire a ton of confidence. The Vols led just 13-6 at halftime before winning by a final score of 30-13.

Florida’s season got off to a disastrous start as it fell behind 17-3 at halftime against Utah in the season opener. The Gators are coming off a 49-7 win over McNeese State as they look to avenge a one-sided loss in Knoxville last year (Florida rallied from a 38-21 deficit to lose just 38-33 at Neyland Stadium in 2022).

Pick: Over .

No. 14 LSU at Mississippi State

  • Time: Saturday, 12:00 p.m. ET
  • TV/Live Stream: ESPN

LSU responded to their Week 1 loss to Florida State with a 72-10 drubbing of Grambling State in Week 2. The Tigers scored 42 points in the first half last week, but they’ll have a much tougher test in Starkville. Mississippi State beat Arizona in overtime in Week 2. MSU is an experienced team playing at home, and veteran Will Rogers and the Bulldogs’ passing game should be able to keep this game close against LSU given the Tigers’ issues in the defensive backfield.

Pick: Mississippi State .

Minnesota at No. 20 North Carolina

  • Time: Saturday, 3:30 p.m. ET
  • TV/Live Stream: ESPN

The Gophers travel to Chapel Hill for a battle between two teams with contrasting approaches offensively. The high-flying Heels are led by their Heisman candidate, QB Drake Maye, while Minnesota relies on its ground game (in Week 2 against Eastern Michigan, the Gophers had 56 rushing attempts compared to just 15 passing). Minnesota was unable to run the ball against Nebraska in the opener and still won 13-10, but they’ll need to find another gear to keep pace with the Tar Heels, who survived a double-overtime battle with in-state foe Appalachian State last Saturday.

Pick: Minnesota .

No. 8 Washington at Michigan State

  • Time: Saturday, 5:00 p.m. ET
  • TV/Live Stream: Peacock

A year ago in Seattle, Huskies QB Michael Penix Jr. and Co. dominated the Spartans for three quarters and led 39-14 with less than 10 minutes to play before giving up two late touchdowns that made the final score, 39-28. This year, Penix and Washington are off to a great start — including blowout wins over Boise State and Tulsa. The Spartans have cruised to easy wins over Central Michigan and Richmond, but they are now dealing with a controversy around their coach, Mel Tucker, who has been suspended amid accusations he sexually harassed rape survivor and activist Brenda Tracy.

Tucker was under considerable pressure before the latest controversy, making it impossible to know what to expect from his team this weekend. What does seem like a safe bet is another big night from Penix, who has already thrown eight touchdowns in two games.

Pick: Over .

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About the Author
Tyler Everett

Tyler Everett

Tyler Everett has been a sports writer since joining the student newspaper at his alma mater, NC State, back in 2008. He's covered sports and sports business for a number of newspapers and websites, including the Denver Broncos, Charlotte Observer, High Press Soccer, and Sports Business Journal, where he currently works full-time.

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