College Football Picks & Parlays for Week 3: SMU-Maryland Look at Sky-High Total is an independent sports news and information service. has partnerships with some of the top legal and licensed sportsbook companies in the US. When you claim a bonus offer or promotion through a link on this site, Gaming Today may receive referral compensation from the sportsbook company. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

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The action during Week 2 did not disappoint, setting the bar for Week 3 pretty high. Bettors have a range of markets to choose from this week, and the following are some of our favorite college football picks and parlays for Week 3 of the 2022 season.

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SMU vs. Maryland Betting Lines: Point Spread, Total, Moneyline, Pick

Maryland can be had for -2.5 as of Friday, and while we’re looking at a sky-high total, we’re going Over 72.5.

VIR Virginia vs SYRA Syracuse Odds NCAAF Odds

NCAAF · Fri (9/23) @ 7:05pm ET

VIR Virginia at SYRA Syracuse
Maryland Stadium, College Park, MD

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SMU (2-0 SU, 2-0 ATS) is starting to look like they could give Cincinnati a run for its money in the AAC this season. Senior quarterback Tanner Mordecai has the offense clicking on all cylinders two weeks into the season. So far, the Mustangs have gained 500+ yards a game and are averaging 46.5 points.

The defense appears to be holding up its end, too. But SMU has yet to play a competitive team — like Maryland (2-0 SU, 2-0 ATS)

The Terps offense has been as explosive as SMU’s through two games, averaging 500+ yards a game and 43.5 points. Junior quarterback Taulia Tagovailoa ranks No. 13 in the country in efficiency (Mordecai ranks No. 11) and has completed an incredible 78.5% of his passes this season.

cfb week 3 picks parlays
Taulia Tagovailoa and Maryland going Over the total is among our college football Week 3 picks (AP Photo/Gail Burton)

Like the Mustangs, the Terps’ defense has been doing a great job. But, like SMU, they have yet to play a competitive team.

Also read: Colorado vs. Minnesota Odds & Pick

Mississippi State vs. LSU Betting Lines: Point Spread, Total, Moneyline, Pick

LSU is laying a tick less than a field goal, per Friday’s oddsboards.

VIR Virginia vs SYRA Syracuse Odds NCAAF Odds

NCAAF · Fri (9/23) @ 7:05pm ET

VIR Virginia at SYRA Syracuse
Tiger Stadium, Baton Rouge, LA

Our Pick: MSST Mississippi State at 9.5 (-108). Bet College Football at FanDuel: Bet $5, Get $150 in Free Bets (Win or Lose)

The Bulldogs are a Mike Leach team, so they are going to throw, throw, and when you think they might do something else, they’ll throw it again. Will Rogers has thrown 49 passes a game and is completing nearly 80 percent of his attempts. On the defensive side of the ball, they’ve dominated their opponents in almost every facet of the game.

But the competition has been soft.

LSU (1-1 SU, 1-1 ATS) struggled in Week 1 against Florida State, but they still nearly came away with a win. Junior quarterback Jayden Daniels showed some flashes of his potential in the game, accounting for 323 yards of offense and two touchdowns. Last week, he was 10-11 for 137 yards and three touchdowns but against a soft opponent.

However, it may be hard to beat a pass-happy team like Mississippi State without putting pressure on the quarterback. The defense recorded three sacks and four tackles for a loss against Southern but failed to record a sack against FSU and only had two tackles for a loss.

Also: Western Kentucky a Live Dog vs. Indiana

Michigan State vs. Washington Betting Lines: Point Spread, Total, Moneyline, Pick

VIR Virginia vs SYRA Syracuse Odds NCAAF Odds

NCAAF · Fri (9/23) @ 7:05pm ET

VIR Virginia at SYRA Syracuse
Husky Stadium, Seattle, WA

Our Pick: WASH Washington at 9.5 (-108). Bet CFB Week 3 at BetMGM: Use promo code TODAY for $1,050 Bonus

Through two games, it appears that Michigan State (2-0 SU, 2-0 ATS) has taken care of the pass-defense issue the Spartans had last year. So far, they are allowing just 198 yards a game while still being dominant against the run (81.5 yards/game). Offensively, they are in good shape as long as the run game can lead the way.

But MSU might be in trouble if they need to throw the ball. Payton Thorne has thrown for just over 200 yards/game and has four touchdowns to his name, along with three interceptions. The Spartans can ground it out in the run game, but they will struggle to keep up in a shootout.

If the Michigan State defense has fixed its issues against the pass, then playing Washington will be a great test. Former Indiana quarterback Michael Penix Jr. has ignited the Husky passing game, averaging 384.5 yards/game. But Washington can also run the ball when they need to (186.5 yards/game this season).

Parlay No. 1 (odds via FanDuel)

While bettors should tread carefully with parlays — a bookmaker’s edge is even greater with parlays than it is with straight bets — it can be fun to sprinkle a few dollars on them. So here’s a look at potential payouts for a few college football Week 3 parlays.

  • Washington -3.5 (-114), Mississippi State -2.5 (-110), Maryland-SMU Over 72.5 (-110)
  • Parlay Odds: +584; a winning $100 wager pays $584

Michigan State is a solid team, but it is not going to run roughshod over the Huskies, and with their lackluster passing game, they will not be able to keep up with Michael Penix Jr. and the Washington pass attack.

LSU is a good team, but it is getting too much credit for playing a decent game against Florida State. In time, the Tigers will be a force to contend with. But for now, they are a team with a lot of new moving parts that are still learning Brian Kelly’s system. Jayden Daniels is a talent, and he’ll make it interesting. But the LSU defense will be no match for Will Rogers once he starts throwing bombs.

The outcome of the Maryland-SMU game is a tough one to judge. Both appear to be clicking on all cylinders, but neither has faced a competitive opponent. Expect this one to be won by whoever has the ball last, which means both teams will score a ton of points.

Parlay No. 2 (odds via DraftKings)

  • Tennessee -46.5 (-110), UConn +47.5 (-105), Ole Miss -17 (-105), Oklahoma -11 (-110), Vanderbilt +115 ML
  • Parlay Odds: +2886
  • Parlay Odds without Vanderbilt: +1289

Dealing with 40+ point spreads poses an additional challenge for sports bettors. Will the favorite win by enough? They probably could, but will they or will they step off the gas and coast once the game is in hand?

Tennessee will crush a poor Akron team with relative ease, with the starters taking care of most of the scoring and the reserves doing enough to cover the spread. But don’t count on Michigan to cover their hefty spread. The Wolverines will have no trouble scoring points and will likely put up another 50-burger. UConn will sneak in a touchdown or two in garbage time and keep the margin of victory in the low 40s.

Georgia Tech has a solid run defense, but it will not help them much against the Ole Miss passing attack. The Georgia Tech defense will keep this one from getting out of hand, but the offense will not be able to do its part. Nebraska is a team in turmoil that can play better than it has been, but not against a solid Oklahoma team this week.

Vanderbilt is not a good team, but the Commodores have been surprisingly competitive this year. They haven’t beaten anyone of consequence and lost by 20 to Wake Forest. But Northern Illinois is not in the same class as the Demon Deacons. It will be a close game that could go either way, but look for Vanderbilt to pull out the win.

About the Author
Travis Pulver

Travis Pulver

Writer and Contributor
Travis Pulver is a Senior Writer for Gaming Today and a lifelong football fan, something he says comes naturally having been born in the football-crazy state of Texas. Through the years, his love of sports has extended into baseball, basketball, golf, and rugby. Life currently finds him in Indiana with his wife and two kids.

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