It’s never too early to talk — or even wager on — football, and bettors can start by taking in odds for Week 1 of the 2022 college football season. The early portion of the season showcases several major programs, including Ohio State, Notre Dame, and LSU.
Opening lines are up at William Hill (rebranded Caesars Sportsbook in most of the country) in Vegas and will soon be available to bettors through mobile sportsbook apps. Notre Dame at Ohio State, and then Oregon vs. Georgia at Mercedes-Benz Stadium in Atlanta, kick off on September 3. Florida State vs. LSU is September 4 at Caesars Superdome in New Orleans.
Week 1 College Football point spreads are up!!! LFG!!! pic.twitter.com/cDuakQImBi
— Brad Powers (@BradPowers7) April 7, 2022
Before placing any wagers, bettors are encouraged to familiarize themselves with the best sportsbook bonuses available. New bettors will be entitled to welcome bonuses and promotions at most leading sportsbooks. Meanwhile, existing customers will find sports-specific promotions, including those offered at the beginning of college football season.
2022 College Football Week 1 Odds
NCAAF · Sat (9/3) @ 12:00 pm ET
| Notre Dame | at | Ohio State |
| Ohio Stadium, Columbus, OH | ||
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Notre Dame vs. Ohio State
Marcus Freeman, 36, is squarely in the spotlight as he transitions from Notre Dame defensive coordinator to head coach. Freeman replaces Brian Kelly, who departed for LSU.
The Fighting Irish take on a different personality — at least internally. Kelly led the program for 12 years, though, so it will take some time before Freeman’s fingerprints are apparent.
Ohio State is led by sophomore sensation C.J. Stroud. The Buckeyes’ signal-caller is the preseason favorite at DraftKings and FanDuel to win the Heisman Trophy. Sophomore wide receiver Jaxon Smith-Njigba is primed to cement himself as the next great Buckeye pass-catcher.
NCAAF · Sat (9/3) @ 3:00 pm ET
| Oregon | at | Georgia |
| Mercedes-Benz Stadium, Atlanta, GA | ||
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Oregon vs. Georgia
Oregon appears to be heading into a buzzsaw to open its 2022 campaign. New head coach Dan Lanning most recently served as Georgia’s defensive coordinator.
Georgia has plenty of reloading to do around a roster that is sending a number of players to the NFL. Regularly securing top-3 recruiting classes makes that task more manageable. The Bulldogs feature talent all over the field, and tight end Brock Bowers is someone to watch in particular. As a freshman in 2021, Bowers finished with a 56-882-13 line, and is another future NFL prospect.
NCAAF · Sun (9/4) @ 8:00 pm ET
| Florida State | at | LSU |
| Caesars Superdome, New Orleans, LA | ||
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Florida State vs. LSU
Though this matchup is technically at a neutral venue, it’s reasonable to expect a pro-Cajun crowd. The Tigers are a combined 11-12 since going undefeated en route to the 2019 National Championship. The LSU faithful will be particularly amped for the full Brian Kelly experience. The Bayou Bengals’ new head coach is tasked with raising the program back to a lofty perch.
Florida State head coach Mike Norvell enters his third season at the helm of the Seminoles’ program. He’s 8-13 overall, but oversaw modest strides in 2021. He’s secured three top-25 recruiting classes since arriving in Tallahassee. However, there’s plenty of work remaining to rehabilitate this former college football power.
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