This week’s Colts vs. Broncos Thursday Night Football player props and TD bets take each team’s injuries into account.
The Broncos lost lead rusher Javonte Williams (knee) for the season. Meanwhile, Jonathan Taylor (ankle) has been ruled out for Week 5 because of a high ankle sprain.
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Indianapolis Colts vs. Denver Broncos TNF Betting Odds
The Broncos are listed as a favorite of between -3 (-115) and -3.5 (even money) the day before kickoff for this Week 5 AFC showdown, with the total ranging between 42.5 and 43.
Both the Colts and Broncos are 1-3 ATS, and the teams combine for a 7-1 mark to the Under. Given the injuries on both sides, the ineffectiveness — especially on offense — demonstrated by each team, and the short week, it’s fair to anticipate a low-scoring contest.
Here are current odds and lines from the US sports betting marketplace.
NFL · Thu (10/6) @ 8:15pm ET
IND Colts | at | DEN Broncos |
Empower Field at Mile High, Denver, Colorado |
Player Prop and Anytime TD Scorer Picks for Week 5 TNF
Russell Wilson Over 225.5 Passing Yards (-115, DraftKings)
Wilson may not be cooking the way many thought he would upon leaving the constraints of Pete Carroll and the Seattle Seahawks. He’s gone Over 225.5 yards twice in four tries, but that was with Javonte Williams in the fold. Without Williams leading the rushing attack, Wilson will presumably shoulder more of the load.

“Next man up” doesn’t apply only to the running backs on the roster. Each of the pass-catchers will need to step up as well.
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Matt Ryan Over 234.5 Passing Yards (-101, Caesars)
Ryan and the Colts are in a similar position with a diminished ground game heading into Thursday night. Ryan will be heavily relied upon as a passer with Taylor sidelined. The Colts have a variety of pass-catchers for Ryan to target throughout the game depending on the situation and what the defense gives him, and the passing volume figures to allow for him to reach 235 passing yards.
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Alec Pierce Over 34.5 Receiving Yards (-101, Caesars)
We discussed the likelihood of Ryan throwing more on Thursday night. We also have to consider Broncos standout cornerback Patrick Surtain II. If he’s deployed primarily against Michael Pittman Jr, the Colts’ top wide receiver, Pierce stands to receive an uptick in attention from Ryan. Considering the ability he’s demonstrated as a downfield threat, an extra target or two could result in an easy Over.
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Courtland Sutton Over 62.5 Receiving Yards (-115, DraftKings)
Sutton doesn’t need too much help right now. He’s earning a 27.8% target share and averaging 14.3 yards per catch. Sutton eclipsed 62.5 yards in three of his four games this season, and drew 10-plus targets on a pair of occasions. Sutton is one of the “next men up” in the wake of Williams’ season-ending injury. Even if his volume doesn’t increase, it should certainly remain as plentiful as it has been in the coming weeks.
Also read: NFL Week 5 Betting Tips
Brandon McManus Over 1.5 Field Goals (-115, DraftKings)
Thursday night contests tend to be offensive slogs, and understandably so. Sportsbooks are pegging this as a low-scoring affair, so it’s reasonable to anticipate a busy night from McManus. He’s received at least two field-goal attempts in three of four games so far this season, and another 2-3 (or more) attempts on Thursday night should be enough for him to convert a pair.
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