Cowboys vs. 49ers Odds, Props, Prediction: Dallas Getting Points in San Francisco on SNF is an independent sports news and information service. has partnerships with some of the top legal and licensed sportsbook companies in the US. When you claim a bonus offer or promotion through a link on this site, Gaming Today may receive referral compensation from the sportsbook company. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

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Two of the favorites to win not only the NFC, but the Super Bowl, meet on Sunday night in Santa Clara, Calif. Dallas travels west at 3-1 after a dominant win over the Patriots, while the 49ers are undefeated, with three of their four wins having been blowouts.

Given the strong starts by both teams and the big stage, this could be one of the highest-rated regular season games of the year, and there’s plenty of betting intrigue as well, with Brock Purdy and Dak Prescott taking on star-studded defenses.


Let’s analyze the Cowboys vs. 49ers odds, props, and a prediction.

More action: NFL Week 5 odds | Super Bowl 58 MVP odds | NFL MVP odds

Cowboys vs. 49ers Spread, Moneyline, Total

Here are the best available NFL odds for moneyline, spread, and total across top sports betting apps. Click on the odds you like to place a bet on. Learn more about sports betting promos when signing up to receive bonus bets.

  • Spread: Cowboys , 49ers
  • Moneyline: Cowboys , 49ers
  • Over/Under: total points

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Cowboys vs. 49ers Betting News

The 49ers, one of the current Super Bowl favorites at , are the home favorites after outscoring their first four opponents by 67 points (125-58). Dallas has dominated three of its first four opponents as well, with a differential of 83 (124-41) despite a loss to Arizona in Week 3.

    • Cowboys, 49ers Super Bowl odds: Cowboys , 49ers
    • Cowboys, 49ers NFC odds: Cowboys , 49ers
    • Cowboys, 49ers division odds: Cowboys (NFC East) , 49ers (NFC West)
    • Cowboys, 49ers season win totals: Cowboys , 49ers
    • Cowboys, 49ers 2023 ATS: Cowboys 3-1, 49ers 3-1
    • Cowboys, 49ers 2023 Over/Under: Cowboys Over 2-2, 49ers Over 2-2

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Cowboys vs. 49ers Props


Here are select prop markets for the game from FanDuel Sportsbook and DraftKings Sportsbook. Live props are available in the above game tiles.

Anytime Touchdown Scorer (FanDuel)

Markets not yet available

1st Half (FanDuel)

  • Cowboys: +2.5 (-105), Moneyline (+134)
  • 49ers: -2.5 (-115), Moneyline (-164)

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Cowboys vs. 49ers Analysis and Prediction

Sunday night’s game in San Francisco should have a playoff atmosphere thanks to the high expectations around both of these teams.

In LB Micah Parsons, who leads an outstanding defense, RB Tony Pollard, WR CeeDee Lamb, and a strong offensive line, Cowboys QB Dak Prescott has one of the best supporting casts in the league. That means that most weeks, as long as Prescott is serviceable, Dallas can win. This week will be a different story, though. The 49ers will likely force Prescott to beat them, and whether he’s up to the challenge will determine whether Dallas can pull the upset.

Dallas struggled offensively against San Francisco in the playoffs in both 2021 and 2022, with the Cowboys losing 23-17 to SF at home in ’21 and 19-12 last year on the road. The Niners limited Prescott to less than 6 yards per attempt in both those meetings, and he’s thrown for two TDS, been picked off three times, and sacked six times in those two games.

The Cowboys’ D will also have a difficult task on Sunday against a balanced 49ers offense led by Christian McCaffrey, who has been unstoppable through four games. Against Arizona in Week 4, McCaffrey turned 27 touches (20 rushes, seven catches) into 177 yards of offense and four TDs, and he’s on pace for easily the best statistical season of his career. Even for defenses that manage to contain McCaffrey, the 49ers boast several other hard-to-defend weapons in Deebo Samuel, Brandon Aiyuk, and George Kittle.

Barring a suffocating performance from the Dallas defense — which is without star corner Trevon Diggs but still has plenty of talent all over the field, from Parsons and DeMarcus Lawrence up front to corners Stephon Gilmore and DaRon Bland on the back end — the 49ers should be able to score enough to stay undefeated in a low-scoring game. Given the total points scored in these teams’ recent playoff matchups was 40 in ’21 and 31 last January, the 49ers (spread) and the Under look like the safest plays.

Pick: 49ers (-3.5 at time of publishing), Under (45 at time of publishing)

How to Watch Cowboys vs. 49ers

  • Date: Sunday, Oct. 8, 2023
  • Time: 8:20 p.m. ET
  • Location: Levi’s Stadium — Santa Clara, Calif.
  • Network: NBC
About the Author
Tyler Everett

Tyler Everett

Tyler Everett has been a sports writer since joining the student newspaper at his alma mater, NC State, back in 2008. He's covered sports and sports business for a number of newspapers and websites, including the Denver Broncos, Charlotte Observer, High Press Soccer, and Sports Business Journal, where he currently works full-time.

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