MLB Player Prop Bets for Bryce Harper, Ronald Acuna Jr. on Friday, Sept. 22 is an independent sports news and information service. has partnerships with some of the top legal and licensed sportsbook companies in the US. When you claim a bonus offer or promotion through a link on this site, Gaming Today may receive referral compensation from the sportsbook company. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

For more information, please read How We Rate Sportsbooks, Privacy Policy, or Contact Us with any concerns you may have.

Gaming Today is licensed and regulated to operate in AR, AZ, CO, CT, DC, IA, IL, IN, KS, LA, MA, MD, MI, NH, NV, NJ, NY, OH, OR, PA, TN, VA, WV & WY.

Happy Friday, and welcome back to another great day of baseball. We have a full 15-game slate tonight, which gives bettors plenty of chances to place an MLB wager, including player props. Here, we will break down our two favorite MLB player prop bets for Friday, Sept. 22. 

Get Up to $1,500 Paid Back in Bonus Bets
UP TO $1,500
In Bonus Bets
$1,500 Paid Back in Bonus Bets
Free Live Streaming - Watch Live Games 
Use Bonus Code: TODAY

Our player prop picks did not produce a winner last night, but we are back with two more props from some of the best hitters in baseball. There are only a handful more games left in the season, which means this is one of the last full slates we get to enjoy and place some bets on. 

Let’s look at the best MLB player prop picks for Friday night.

MoreWorld Series odds | MLB betting promotions | MLB MVP odds | Run line betting

Tonight’s MLB Odds

Here are the betting odds from the top sports betting apps for the games in which we have a player prop bet. Before placing your bets, also check out our MLB odds page to ensure you get the best numbers for your wagers and browse the best MLB betting sites



Bryce Harper Over Total Bases

Bryce Harper‘s season did not start until May, as he was recovering from UCL surgery in the offseason. While he batted .315 in his first month of games, he was not hitting the ball as hard as he usually does. 

In August, Harper found his power stroke, as he put up 10 home runs and had a .423 ISO with a Barrel% of 23%. This month, he is slumping a little bit, but his bat has been more active over the last 10 games, as he is slashing .243/.404/.595 with four home runs and a .420 wOBA. 

Tonight, he faces a struggling Mets team that is just trying to cross the finish line at this point. New York will send out Tylor Megill tonight, and while he has gotten the best of Harper in six career ABs, he has not been very good this season and is due for some significant regression. 

Megill also struggles against left-handed hitters, allowing a slash of .303/.382/.465. In this spot, with Harper starting to heat up and against a bad Mets pitching staff, he should be in for a big night. 

Get up to $1,000 at Caesars Sportsbook
$1,000 FIRST BET
On Caesars
Up to $1,000 Back as a Bonus Bet if Your Bet Loses
Stream NFL Games In-App for Free
21+ Gambling problem? Call 1-800-GAMBLER
Use Promo Code: TODAY1000

Ronald Acuna Jr Over Total Bases

The likely NL MVP is wrapping up a historic season. For the first time in baseball history, a player has hit 30+ home runs and has 60+ steals. He may not be done making history, however, as Ronald Acuna Jr. is just one home run and two stolen bases away from being the first member of the 40-70 club as well. 

It seems like Acuna is making history almost every single day, and it is not hard to see why. He enters tonight with 39 home runs, 100 RBI, and 140 runs. He also is slashing .335/.414/.592, which are career-highs across the board, and he ranks third in fWAR (7.6), just behind Shohei Ohtani and Mookie Betts. 

Acuna has a hit in seven straight games, and during that time, he has a slash of .3643/.371/.727 with a .448 wOBA and three home runs. After a somewhat down year last season, Acuna is also back to mashing lefties, and he has one of the worst left-handed pitchers in baseball on the mound tonight. 

Washington will send out Patrick Corbin, who continues to be shockingly terrible. Ever since his key contributions to the 2019 World Series Championship team, Corbin has not had an ERA below 4.66, is not striking guys out at a high clip anymore, and is giving up a ton of hard contact, especially to right-handed hitters. 

The Nationals surprised people with how frisky they were this season, especially during summer. However, the pitching is still a nightmare, and Acuna and the rest of this unbelievably talented Braves’ lineup should feast in this game. 

MLB Player Prop Parlay

You can parlay our MLB player prop bets to maximize your winnings for tonight’s action. At FanDuel, our prop picks parlayed would give you +251 odds at the time of this publication. That is a nice chunk of change you would get if both MLB player props cash. 

New Players get up to $150 in Bonus Bets at FanDuel Sportsbook
Bet $5
Get $150
In Bonus Bets
Up to $150 in Bonus Bets if Your Team Wins
Available on Desktop, Android & iOS
To Claim: Click Play Now

Best MLB Sports Betting Bonuses

Check out each sportsbook’s bonus offers before placing your MLB player prop bets. Each sportsbook you sign up with opens you up to hundreds of dollars in bonus bets, which can help build your bankroll for a long MLB season. 

Here are the best sportsbook bonuses from the top US sports betting apps at Gaming Today.

📱Sportsbook 💰Welcome Offer🎯 Promo Code⭐️Why We Like It🇺🇸 Availability
📱Caesars💰Get up to a $1,000 First Bet on Caesars🎯 Click to claim with code TODAY1000⭐️ Best for rewards🇺🇸 AZ, CO, IN, IL, IA, KS, KY, LA, ME, MD, MA, MI, NJ, NY, OH, PA, TN, VA & WV
📱BetMGM💰Get up to $1,500 in Bonus Bets, if you don't win. New Customers in MI, NJ, PA & WV use bonus code GETTODAY to Bet $10 on any NFL game and Win $200 in Bonus Bets Instantly🎯 Click to claim with code TODAY OR GETTODAY ⭐️ Best for new bettors🇺🇸 AZ, CO, DC, IL, IN, IA, KS, KY, LA, MA, MD, MI, MS, NJ, OH, NV, NY, PA, TN, VA, WV & WY - Note: Offer not available in DC, MS, NV or NY
📱BetRivers💰Get a Second Chance Bet Credit up to $500 ($100 in AZ, IA, NY, OH, & WV; $250 in CO & NJ)🎯 Click to claim with code TODAYRIV⭐️ Best sports-based profit boosts🇺🇸 AZ, CO, IL, IN, IA, LA, MD, MI, OH, NJ, NY, PA, VA & WV
📱FanDuel💰Bet $5 on any Moneyline, Get $150 in Bonus Bets if you team wins🎯 Click to Claim⭐️ Best overall app (iOS & Android)🇺🇸 AZ, CO, IL, IN, IA, KS, KY, LA, MA, MD, MI, NJ, NY, OH, PA, TN, VA, WV & WY
📱Bet365💰First Bet Safety Net up to $1,000 OR Bet $5, Get $150 in Bonus Bets🎯 Use Code GTODAYVA⭐️ Best variety of betting markets🇺🇸 CO, IA, KY, LA, NJ, OH & VA
📱DraftKings💰Claim up to $1,200 in Bonus Offers🎯 Click to Claim⭐️ Best ongoing promotions🇺🇸 AZ, CO, CT, IL, IN, IA, KS, KY, LA, ME, MD, MA, MI, NH, NJ, NY, OH, PA, TN, VA, WV & WY

About the Author
DJ Corrigan

DJ Corrigan

DJ Corrigan is a sports betting writer for Gaming Today and has been covering the world of wagering since his days at Ohio State University. Corrigan's love of betting the Over and chasing the hungry dogs has led him to a career crunching numbers with an emphasis on NCAAF, NCAAB, NFL, and MLB betting.

Get connected with us on Social Media