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The Detroit Lions (1-4) are coming off a much-needed Week 6 bye after getting shut out by New England. They now travel to Texas to face the Dallas Cowboys (4-2), who will be welcoming back a very important player.

Dallas quarterback Dak Prescott makes his way back into the lineup after being sidelined for four weeks with a thumb injury on his throwing hand. As a result, Dallas is laying a full TD against the Lions at DraftKings in what feels like a homecoming game for the starting QB.

Below, we look at Lions vs. Cowboys odds and give our prediction for this all-NFC Week 7 matchup.

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Detroit Lions vs. Dallas Cowboys Betting Lines

Oddsmakers favor America’s Team – priced between -300 and -335 on the moneyline as of Wednesday morning – to win by a touchdown against Detroit. DraftKings is dealing the longest odds at +270 for the Lions to pull off the upset.

Here are the best current Lions vs. Cowboys moneyline, spread, and total lines among top sportsbooks.

DET Lions vs DAL Cowboys Odds NFL Odds

NFL · Sun (10/23) @ 1:00pm ET

DET Lions at DAL Cowboys
AT&T Stadium, Arlington, TX

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The Cowboys have won their last four games against Detroit, including three straight with Prescott under center. The total for this game is between 48 and 48.5 across the board.

Lions vs. Cowboys Betting Preview


The Lions dropped a goose egg in Foxborough after leading the NFL in scoring through the first four weeks. The offense is still regarded as one of the best in the league, though a 1-5 record is all the team has to show for it.

Detroit’s woeful 2022 season can be blamed on its defense, which ranks dead last in both yards (428.6 per game) and scoring (34.0 points per game).

The team used the bye week to regain some health. Running back D’Andre Swift is expected to return this week after sitting out the past two contests with a shoulder injury. Top receiver Amon-Ra St. Brown limped into his Week 5 matchup with a less-than-healthy ankle, and it fully showed (four catches for 18 yards). Wideout DJ Chark (ankle) also missed the last game.

No one expects the defense to suddenly become less of a disaster after its bye. It still poses no threat whatsoever against a Prescott-led offense.

The run game will give the Lions a puncher’s chance in this matchup, and it all starts with Swift’s health. Detroit averages 151.4 yards rushing per contest (eighth in the NFL), but that number jumps up to a whopping 184.7 in games featuring Swift.

Also read: NFL Week 7 Betting Tips & Strategies: Back These Underdogs


The Cowboys’ so-called “quarterback controversy” was finally put to rest after interim quarterback Cooper Rush got exposed (three interceptions, 32.2 QBR) against the undefeated Philadelphia Eagles in Week 6.

Dallas enjoyed its time with Rush as caretaker, but Prescott has been aching (in desire, not in his thumb) to return to action for over five weeks now. The last time we saw Prescott grace the field was in the season opener against the Tampa Bay Buccaneers in what might have been the worst performance of the seven-year vet’s career.

The Dallas Cowboys are favored by a touchdown against the Detroit Lions this Sunday as quarterback Dak Prescott returns to the lineup. (Photo by Scott W. Grau/Icon Sportswire)

On the other hand, the defense, particularly against the pass, was stellar in Week 1 as it has been all season. Led by 2022 Defensive Player of the Year favorite Micah Parsons, Dallas ranks third in the league in both scoring defense (16.3 per contest) and yards per pass attempt (5.2).

The Cowboys have held five of their six opponents to under 20 points, though they haven’t faced an offensive unit as high-flying as the Lions.

Lions vs. Cowboys Betting Trends

Bettors have had great success wagering on Dallas, both on the moneyline and the spread.

When it comes to the betting on the point total, Lions games often crush the Over, whereas Cowboys games lean heavily towards the Under.


  • 1-4 moneyline overall; 1-2 ML at home; 0-2 ML on the road
  • 3-2 ATS overall; 2-1 ATS at home; 1-1 ATS on the road
  • 4-1 O/U overall; 3-0 O/U at home; 1-1 O/U on the road
  • 0-1 ATS as favorite; 3-1 ATS as underdog


  • 4-2 ML overall; 2-1 ML at home; 2-1 ML on the road
  • 4-2 ATS overall; 2-1 ATS at home; 2-1 ATS on the road
  • 2-4 O/U overall; 0-3 O/U at home; 2-1 O/U on the road
  • 1-0 ATS as favorite; 3-2 ATS as underdog

Lions vs. Cowboys Prediction

Get ready for fireworks at AT&T Stadium this weekend, because a bunch of points will be scored by both squads.

Rush played well enough to win four out of the last five games this season, but he’s been unable to blow opponents out. Dallas ranks 23rd in scoring offense (18.3 per game) and 27th in total passing yards (182.0 per game) – a recipe for close, low-scoring ball games.

Prescott gives this Cowboys offense that extra punch. He’s a dynamic thrower who can surely help slap a ton of points onto the scoreboard, especially against the worst defense in the league in Detroit.

Expect a fully healthy Prescott to come in and lead America’s Team to a decisive victory against the visitors. The Lions will find themselves down heavily entering the fourth quarter and play a meaningless game of catchup, only to fall way short of winning.

Prediction: Cowboys 34, Lions 23 

Lions vs. Cowboys Broadcast Information

  • Location: AT&T Stadium in Arlington, TX
  • Date/Time: Sunday, October 23; 1:00 p.m. ET
  • Where to Watch: CBS

Read more: NFL Week 7 odds  | Bookies Battle 2022 Recap & Week 7 Lines

About the Author
Cyrus Eshaghoff

Cyrus Eshaghoff

Cyrus Eshaghoff is a New York-based sports betting writer at Gaming Today who covers the UFC, NFL, and NBA. Whether it's heated debates or uncovering statistical insights, he loves discussing (and writing about) sports.

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