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Week 2 of the NFL season got off to an exciting start with an excellent game between the Kansas City Chiefs and Los Angeles Chargers Thursday night. There are more great games on deck this Sunday with plenty of markets for bettors to enjoy and combine to make parlay bets. Let’s examine a few of our favorite NFL parlay picks and a same-game parlay bet for Week 2.

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NFL Parlays: What to Know

When you make your NFL parlay picks this week, it is important to keep two things in mind: 1) sportsbooks generally have a greater edge with parlays than with straight bets. Tread lightly and have fun, but don’t fool yourself into believing the the large potential payouts flip the advantage to the bettor; 2) Do not overreact to what happened in Week 1. That is the only reference point for how good a team might be, but it is not uncommon for a team to stumble out of the gate and then get their act together in Week 2.

With so many teams not playing their starters during the preseason, they are knocking off the rust in Week 1. Some have more rust than others. In some cases, new teammates have not worked together enough for an offense/defense to operate smoothly and efficiently.

So, don’t assume the Packers are garbage or that the Giants are competitive, or that the Broncos made a mistake going after Russell Wilson just yet. We do not have enough information to come to those conclusions (yet).

For more: Best NFL parlay apps | Learn more about parlay betting odds

NFL Week 2 Parlay No. 1

Let’s start with an NFL parlay with picks one of our writer Ken Bates made in an article published this week:

A $100 wager on this NFL parlay will result in a $695 payout (your $100 plus $595 in winnings)

It may be tempting to think the Bears have a shot to make it a competitive game, but they will not have the benefit of playing in a massive rainstorm this week. Yes, Green Bay looked terrible last week against the Vikings. But they looked awful in Week 1 last year, too. Aaron Rodgers responded by going 22-for-27 for 255 yards and four touchdowns in a 35-17 win over the Lions.

Chicago is one team Aaron Rodgers has dominated over the years.

The Saints have owned the Buccaneers in recent years, winning seven of the last eight meetings between the two teams (7-1 ATS, too). Dennis Allen was the acting head coach last year when the Saints beat the Bucs, 9-0. So, he knows how to game plan for Tom Brady and the Bucs offense.

It will be a close game, one the Saints could win straight up or against the spread.

The Falcons were competitive against the Saints last week and even led most of the game. But the Rams’ defense is a different challenge, as is their offense—assuming the offense gets on track. Matthew Stafford and the O struggled in Week 1 (vs. the Bills). They’ll be better this week, but don’t count on them to run up the score.

Aaron Donald and the rest of the Rams’ D will keep the Falcons from scoring much.

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NFL Week 2 Parlay No. 2

  • Jets-Browns: Under 39 (-110)
  • Commanders-Lions: Lions -1.5 (-110)
  • Panthers-Giants: Giants -1.5 (-110)
  • Seahawks-49ers: Seahawks +8.5 (-110)
  • Texans-Broncos: Texans +10 (-110)
  • Parlay Odds: +2435

(odds via BetMGM)

This is a more ambitious NFL parlay, but if it hits, we are talking about a pretty nice payday. A $100 wager would get you a $2,535 payout (your $100 stake and $2435 in winnings).

Fans were hoping this could be the year the Jets climb out of the cellar, but that does not appear to be the case after Week 1. Joe Flacco was solid in his day, but he’s been passed by. The Jets’ offense will struggle against the Cleveland D and could get shut out. Cleveland’s offense will score, but it isn’t good enough to score a lot.

Taking the Lions may feel strange, but this Detroit team is not our daddy’s Lions team. These guys are not half-bad. While they fell behind early to the Philadelphia Eagles, they battled back and made it interesting in the end. Washington needed a Trevor Lawrence turnover to beat the Jaguars.

Carolina put up a fight against Cleveland last week but fell short, partly because they couldn’t stop the run. This could mean Saquon Barkley is in for a good day for the second consecutive week. Washington’s passing game will keep them in it, but they will not get the present (turnover) from the Giants they got from the Jaguars.

As for the Seahawks-49ers, this pick is a leap of faith. Geno Smith has never played as well as last week, but he has also had time to work with the offense as the starting quarterback. A solid supporting cast surrounds him.

Not playing in a monsoon could do wonders for the 49ers, but is Trey Lance ready? Eh.

Don’t count on Houston to beat the Denver Broncos. However, do count on them to be more competitive than expected. They put up a solid fight against a good Colts team last week, especially the defense. Russell Wilson and the Denver offense are still working out the kinks, which opens the door for the Texans to keep this one in single digits.

Also readEarly Week 2 betting trends at sportsbooks

NFL Parlay No. 3: A Week 2 Same-Game Parlay (odds via DraftKings)

  • Joe Burrow Over 304.5 passing yards +210
  • Joe Mixon Over 74.5 rushing yards -105
  • Ja’Marr Chase anytime touchdown scorer -135
  • Joe Mixon anytime touchdown scorer -130
  • Parlay Odds: +1000

A $100 bet on this parlay would result in an $1100 payout, should it be a winner (your stake plus $1000 in winnings).

Dallas is a team in turmoil. The offense was not looking good with Dak Prescott; it will look worse without him this week. The defense will keep the Cowboys in the game for the first half, but the Bengals will blow the game open in the second once they wear the Dallas D down. After losing last week, Joe Burrow and the Bengals will want to prove themselves this week.

The Cowboys may be able to slow the Bengals down. But since the defense will be on the field for most of the game, they will not stop them.

More action: NFL Week 2 Player Props and TD Scorer Bets

(AP Photo/Kirk Irwin)

About the Author
Travis Pulver

Travis Pulver

Senior Writer
Travis Pulver is a senior writer for Gaming Today and a lifelong football fan, something he says comes naturally having been born in the football-crazy state of Texas. Through the years, Pulver's love of sports has extended into baseball, basketball, golf, and rugby. Life currently finds him in Indiana with his wife and two kids.

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