While the Commanders-Bears game was not much fun to watch on Thursday night, it was a great game to bet on (two low-scoring teams with struggling offenses). That game is in the books, which means it’s time to examine the remaining games and markets for Week 6, many of which bettors can combine to form NFL parlay bets.
There is more risk with NFL parlay bets than just betting on an individual game, but with the risk comes the possibility of a greater reward. Here are a few of our favorite NFL parlay picks for Week 6, including a couple of same-game parlay bets.
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NFL Parlay Picks: Week 6 (odds via FanDuel)
Parlays can be a lot of fun – and profitable. But you have to be careful with them. It can be easy to get greedy and add one extra leg to a parlay to make the potential payday bigger. But you are better off keeping them shorter. You may not win as much with a two or three-leg parlay as a six-leg one, but you have a better chance of actually winning.
We’re featuring FanDuel odds this week, but you should always compare the odds at other top sports betting apps.
Let’s go over a few options:
NFL Parlay No. 1: A 2-Legged 49ers vs. Falcons Same-Game Play
- Jimmy Garoppolo – Over 228.5 yards (-114)
- Total – Under 44.5 points (-110)
- Parlay odds – +319
San Francisco is a run-first team, but the passing attack has improved each week under Jimmy Garoppolo. After watching how Tom Brady decimated the Falcons’ secondary last week, Kyle Shanahan will probably not hesitate to throw the ball a little more. Since taking over as the starter, Garoppolo has thrown for 211, 239, and 253 yards. Atlanta is allowing an average of 278.2 passing yards a game.

As for the score, the 49ers will not have much trouble dominating an Atlanta offense missing its best weapon (Cordarrelle Paterson). It would not be shocking if they pitched a shutout this week. San Francisco’s offense will score enough to win but does not seem to score a lot (they average 21.6/per game).
A $100 bet would result in a $419 payday, your stake plus $319 in winnings.
Also read: Broncos vs. Chargers | Cowboys vs. Eagles | Bills vs. Chiefs
NFL Parlay No. 2: Cowboys vs. Eagles Same-Game Parlay Picks
- Total – Under 42.5 (-114)
- Cooper Rush – Under 218.5 passing yards (-118)
- Jalen Hurts – Anytime Touchdown Scorer (+115)
- Parlay Odds – +732
Cooper Rush has done an admirable job the last few weeks, but the team has not asked him to win games. It’s been the run game and the defense that has saved the day. Against a tough Philly defense, that will likely be the case this week, too. The Eagles have allowed an average of 189 yards a game this season, making it unlikely Rush throws for more than 218.5.
Hurts has recorded a rushing touchdown in every game but one this season (vs. Washington). Dallas has been tough to score on this season (avg. 14.4 points allowed/game), but they are not tough to run on (117.6 yards/game allowed). Philly will need its budding superstar to make a few plays to win this game. Don’t be shocked if he breaks off a 20+ yard touchdown run.
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As for the score, Dallas struggles to score points and will probably struggle even more against a solid Philly defense. The Eagles can score some points but will find it tough sledding against the Dallas D.
A $100 bet would result in an $832 payday, your stake plus $732 in winnings.
NFL Parlay No. 3: Brady, Rodgers With Opposite Outlooks in Player Prop Parlay
- Tom Brady – Over 280.5 passing yards (-114)
- Aaron Rodgers – Under 242.5 passing yards (-114)
- Stefon Diggs – Anytime Touchdown Scorer (-115)
- Parlay Odds – +558
Click to Bet on NFL Parlays at FanDuel Today
The Buccaneers have been leaning heavily on Tom Brady in recent weeks and against a lackluster Pittsburgh defense, they will likely do the same. Teams are averaging 287.6 yards against the Steeler D; Brady has thrown for 350+ in his last two.
It may seem strange to take the under on Aaron Rodgers, but the Packers’ offense has sputtered this season. Rodgers has thrown for 195,234, 255, 251, and 222 yards this season. The Jets’ defense is pretty decent; it’s only allowing 205.8 passing yards a game.
Kansas City and Buffalo’s playoff game was a barn burner last season, with the two teams combining for 700+ yards and seven touchdowns in the passing game. There is no reason to think Sunday’s game will be any different. Diggs didn’t score in the playoff game but expect Josh Allen to target his No. 1 in the end zone early and often.
A $100 bet would result in a $668 payday, your stake plus $558 in winnings.
Bookmark these: Best NFL parlay apps | Learn more about parlay betting odds | How to bet on NFL games