It’s time to update NFL Week 13 odds for a 15-game slate includes Titans-Eagles, Chiefs-Bengals, and Dolphins-49ers. The Buffalo Bills got Week 13 started with a 24-10 win over the New England Patriots on TNF.
Here we examine line movement at DraftKings, which released its opening lines on Sunday. The Arizona Cardinals and Carolina Panthers are on a bye week.
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NFL Week 13 Betting Lines
Here are betting lines for Week 13 games from across the sports betting marketplace.
NFL Week 13 Odds
Let’s take a game-by-game peek at NFL Week 13 betting lines from DraftKings, current as of Dec. 2.
Titans at Eagles (-4.5, 44)
This line opened at Philadelphia -6.5, but Tennessee backers dropped it two points during the week. The Titans have covered their last five road games.
One of the most surprising moves last off-season came when Tennessee traded star WR A.J. Brown to Philadelphia. Brown will face his former mates in one of Week 13’s biggest tilts.

The Titans had covered their last eight games ATS before last week’s 20-16 loss to the Bengals. Philadelphia ran its record to an NFL-best 10-1 with a 40-33 win over Green Bay. The Eagles also covered the number as 6.5-point favorites.
Chiefs (-1.5, 52.5) at Bengals
Some movement toward the home dog here after an opener of Kansas City -3. Home dogs are 40-30-3 ATS this season, hitting at a clip of of 57.1%.
Bengals WR Ja’Marr Chase (hip) is expected to be back in the starting lineup for this huge home tilt against the Chiefs. Chase torched KC’s secondary for 266 receiving yards and three TDs in a 34-31 win over the Chiefs in the regular season last year.
The Chiefs have been road warriors this season, going 4-1 overall and 3-2 ATS.
Packers (-3.5, 44.5) at Bears
Injuries and uncertainty at the QB position for both teams here. Chicago’s Justin Fields (shoulder) was reportedly a full participant in practice yesterday after being limited on Wednesday. Aaron Rodgers (thumb/ribs) also returned to drills on Thursday. Rodgers is 23-5 against the Bears in his career.
Jets at Vikings (-3, 44.5)
The total climbed 2.5 points from an opener of 42. These two teams will meet for the first time since 2018. The Jets have been money on the road this year, winning and covering four of five games.
Commanders (-2.5, 40) at Giants
The Commanders received some support after opening -1 on Sunday. In a scheduling quirk, Washington and New York face each other in Week 13 and then again in Week 15 with a bye week sandwiched in between for both teams. The Commanders are 6-0-1 ATS in their last seven games.
Seahawks (-7, 41) at Rams
Major movement here in the direction of Seattle after an opener of Seahawks -4.5. Fortunes have flipped for these two NFC West franchises. The Seahawks were predicted to finish dead last in the division heading into the season. That’s where the Rams (3-8) find themselves through Week 11. Seattle (6-5) is one game in back of San Francisco for the division lead.
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Dolphins at 49ers (-4, 46.5)
The Tua-led Dolphins have won and covered their last two road games against Chicago and Detroit, but this is clear step up in class at San Francisco. The 49ers are particularly tough at home, going 8-1 SU in their last nine games. Miami is riding a five-game winning streak.
Chargers at Raiders (-1, 50.5)
This line flipped from an opener of Chargers -2.5. Los Angeles WR Mike Williams (ankle) did not practice Wednesday or Thursday. The Chargers have covered three of their last four games. The Raiders have won and covered their last two after a 40-34 shootout win at Seattle last week.
Colts at Cowboys (-10.5, 44) — SNF
This is the biggest spread on the Week 13 betting board. Dallas opened -9 and the public loves backing the ‘Boys. Dallas has only been a double-digit favorite once previously this season. The Cowboys were favored similarly over the Giants and failed to cover in a 28-20 win on Thanksgiving.
Saints at Buccaneers (-4, 40.5) — MNF
Some love for the Saints here after Tampa Bay opened -5.5. Tampa Bay reversed the recent trend in this series with a 20-10 win at New Orleans in Week 2. The Saints swept the season series last year.
The Bucs have yet to cover an actual home game at Raymond James Stadium this season, going 0-4-1 against the number. Tampa Bay covered as the “home” team in Munich with a 21-16 win over the Seahawks.
The Rest of NFL Week 13 Games
Steelers at Falcons (-1, 42.5)
Jaguars (-1, 51) at Lions
Browns (-7, 47.5) at Texans
Broncos at Ravens (-8.5, 39.5)
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