NFL Week 15 Odds: Bills a Healthy Home Favorite vs. Dolphins

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It’s time to check on NFL Week 15 odds and see how betting lines have moved for the full slate.

This marks the first week of the season when games will be played on Thursday, Saturday, Sunday, and Monday. The 49ers beat the Seahawks, 21-13, to start the week on TNF.

Dolphins-Bills highlights a trio of games on Saturday, Dec. 17.

Let’s take a look at NFL Week 15 odds.

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NFL Week 15 Betting Lines

Here’s are a look at odds for Week 15 games from the best sports betting apps.

Bet TypeSpreads
Open
Thu (12/14) @ 8:16pm ET LA Chargers +125 +4000 +3300 +3500 +135 +3500 +6600
LV Raiders -149 0 -10000 0 -164 0 0
Sat (12/16) @ 1:02pm ET MIN Vikings +165 +1800 +1200 +1400 +1700 +1700
CIN Bengals -200 -5000 -3333 -5000 -10000 -5000
Sat (12/16) @ 4:33pm ET PIT Steelers +115 +4000 +1150 +6000 -105 +1500 +1400
IND Colts -141 0 -3333 0 -118 -10000 -5000
Sat (12/16) @ 8:15pm ET DEN Broncos +165 +4000 +3300 +2200 +2500 +3500
DET Lions -200 0 -10000 -10000 0 0
Sun (12/17) @ 1:02pm ET ATL Falcons -164 +1800 +500 +550 -149 +240 0
CAR Panthers +140 -5000 -769 -909 +130 -333 0
Sun (12/17) @ 1:02pm ET NY Jets +425 +3000 +3300 +4500 +2000 +10000
MIA Dolphins -588 0 -10000 0 0 0
Sun (12/17) @ 1:02pm ET HOU Texans +105 +230 -10000 +230 -345 -1250
TEN Titans -125 -313 +2000 -303 +255 +550
Sun (12/17) @ 1:02pm ET CHI Bears +145 +520 +600 +1100 +1300 0
CLE Browns -175 -833 -1111 -3333 -5000 0
Sun (12/17) @ 1:02pm ET TB Buccaneers +165 -10000 -10000 -556 -5000 0
GB Packers -200 +2000 +3300 +380 +1400 0
Sun (12/17) @ 1:02pm ET NY Giants +225 +1600 +3300 +1100 +1300 +6600
NO Saints -278 -5000 -10000 -3333 -5000 0
Sun (12/17) @ 1:03pm ET KC Chiefs -455 0 -10000 -1250 -455 0 0
NE Patriots +340 +4000 +3300 +700 +320 +4000 +9000
Sun (12/17) @ 4:05pm ET WAS Commanders +240 +3000 +1400 +1100 +235 +900 +4000
LA Rams -303 0 -10000 -3333 -303 -2500 0
Sun (12/17) @ 4:05pm ET SF 49ers -833 -10000 -10000 0 -769 -10000 0
ARI Cardinals +550 +2000 +1850 +5000 +525 +1500 +6000
Sun (12/17) @ 4:26pm ET DAL Cowboys +105 +3000 +3300 +900 +118 +3500 +5000
BUF Bills -125 0 -10000 -2000 -137 0 0
Sun (12/17) @ 8:22pm ET BAL Ravens -185 -5000 -10000 -5000 -208 -5000 0
JAX Jaguars +150 +1600 +3300 +1200 +170 +1300 0
Mon (12/18) @ 8:15pm ET PHI Eagles -189 +450 +400 +280 +520 +450
SEA Seahawks +155 -714 -667 -385 -909 -833
Thu (12/14) @ 8:16pm ET LA Chargers +3.0 -110 +48.5 +124 +41.5 +900 +42.0 0 +3.0 -118 +42.5 -128 +42.0 0
LV Raiders -3.0 -110 -48.5 -161 -41.5 -2500 -42.0 +5000 -3.0 -104 -42.5 -102 -42.0 0
Sat (12/16) @ 1:02pm ET MIN Vikings +5.0 -110 -6.5 -189 -6.5 -141 -6.5 -145 +3.0 0
CIN Bengals -5.0 -110 +6.5 +145 +6.5 +110 +6.5 +110 -3.0 0
Sat (12/16) @ 4:33pm ET PIT Steelers +2.5 -110 +16.5 +1300 +16.5 +155 +17.0 -556 +1.0 -110 +12.5 +880 +14.0 -250
IND Colts -2.5 -110 -16.5 -3333 -16.5 -208 -17.0 +380 -1.0 -110 -12.5 -2500 -14.0 +190
Sat (12/16) @ 8:15pm ET DEN Broncos +4.0 -110 +24.5 +310 +24.5 +450 +24.5 +1200 +24.5 +325 +24.5 +250
DET Lions -4.0 -110 -24.5 -455 -24.5 -769 -24.5 -5000 -24.5 -500 -24.5 -345
Sun (12/17) @ 1:02pm ET ATL Falcons -3.0 -110 -1.5 +114 -1.5 +160 -1.5 +135 -3.0 -110 +1.5 -313 -1.0 -105
CAR Panthers +3.0 -110 +1.5 -145 +1.5 -208 +1.5 -169 +3.0 -120 -1.5 +225 +1.0 -120
Sun (12/17) @ 1:02pm ET NY Jets +12.0 -110 +30.5 -3333 +29.5 +900 +30.5 -400 +29.5 +410 +30.0 -200
MIA Dolphins -12.0 -110 -30.5 +1300 -29.5 -2500 -30.5 +290 -29.5 -667 -30.0 +160
Sun (12/17) @ 1:02pm ET HOU Texans +1.5 -110 -1.5 -141 +6.5 +140 +6.5 +180 +6.5 +138 +7.0 -175
TEN Titans -1.5 -110 +1.5 +110 -6.5 -185 -6.5 -233 -6.5 -182 -7.0 +140
Sun (12/17) @ 1:02pm ET CHI Bears +3.0 -105 -6.5 -179 +2.5 -105 -6.5 -145 -6.5 -154 +0.5 -120
CLE Browns -3.0 -115 +6.5 +140 -2.5 -125 +6.5 +115 +6.5 +118 -0.5 -105
Sun (12/17) @ 1:02pm ET TB Buccaneers +3.5 -110 -14.5 +600 -14.5 +250 -14.5 +200 -14.5 +285 -14.0 -323
GB Packers -3.5 -110 +14.5 -1000 +14.5 -345 +14.5 -263 +14.5 -417 +14.0 +240
Sun (12/17) @ 1:02pm ET NY Giants +6.0 -110 +15.5 -145 +15.5 +3300 +18.0 +200 +18.5 -278 +17.5 +210
NO Saints -6.0 -110 -15.5 +114 -15.5 -10000 -18.0 -263 -18.5 +205 -17.5 -278
Sun (12/17) @ 1:03pm ET KC Chiefs -9.5 -110 -16.5 -213 -13.5 +240 -16.5 -400 -10.0 -109 -16.5 -213 -12.5 -112
NE Patriots +9.5 -110 +16.5 +165 +13.5 -345 +16.5 +290 +10.0 -112 +16.5 +162 +12.5 -112
Sun (12/17) @ 4:05pm ET WAS Commanders +16.5 -130 +19.5 -115 +20.5 +115 +8.0 +1000 +6.5 -108 +7.5 +630 +20.5 +105
LA Rams -16.5 +100 -19.5 -115 -20.5 -149 -8.0 -2500 -6.5 -114 -7.5 -1250 -20.5 -130
Sun (12/17) @ 4:05pm ET SF 49ers -14.0 -110 -16.5 -115 -17.5 -115 -16.0 -278 -11.0 -114 -22.5 -179 -19.5 -200
ARI Cardinals +14.0 -110 +16.5 -115 +17.5 -115 +16.0 +215 +11.0 -108 +22.5 +136 +19.5 +160
Sun (12/17) @ 4:26pm ET DAL Cowboys +1.5 -110 +20.5 +2000 +20.5 +1700 +20.0 +1800 +2.5 -114 +21.5 -213 +21.0 0
BUF Bills -1.5 -110 -20.5 -10000 -20.5 -10000 -20.0 -5000 -2.5 -115 -21.5 +162 -21.0 0
Sun (12/17) @ 8:22pm ET BAL Ravens -3.5 -110 -15.5 -1429 -16.5 +200 -16.0 -105 -4.0 -110 -15.5 -1250 -16.0 0
JAX Jaguars +3.5 -110 +15.5 +750 +16.5 -278 +16.0 -125 +4.0 -110 +15.5 +630 +16.0 0
Mon (12/18) @ 8:15pm ET PHI Eagles -3.5 -110 +2.5 +380 -4.5 +300 -4.5 +240 -4.5 +430 -4.0 0
SEA Seahawks +3.5 -110 -2.5 -588 +4.5 -455 +4.5 -323 +4.5 -714 +4.0 0
Thu (12/14) @ 8:16pm ET LA Chargers u34.5 -110 u84.5 0 u84.5 -10000 u36 -110 u36.0 -110 u77.5 -147 u76.5 +135
LV Raiders o34.5 -110 o84.5 +4000 o84.5 +1550 o36 -110 o36.0 -110 o77.5 +114 o76.5 -169
Sat (12/16) @ 1:02pm ET MIN Vikings u39.5 -105 u39.5 -110 u50.5 +1350 u40.5 -135 u44.5 -120
CIN Bengals o39.5 -115 o39.5 -120 o50.5 -10000 o40.5 +104 o44.5 -105
Sat (12/16) @ 4:33pm ET PIT Steelers u42.5 -110 u42.5 +300 u43.5 -149 u41.5 -110 u41.5 -108 u43.5 -122 u43.5 -120
IND Colts o42.5 -110 o42.5 -417 o43.5 +115 o41.5 -110 o41.5 -114 o43.5 -106 o43.5 -105
Sat (12/16) @ 8:15pm ET DEN Broncos o46.5 -110 o59.5 +325 o52.5 +125 o52.5 +100 o51.5 -125
DET Lions u46.5 -110 u59.5 -476 u52.5 -164 u52.5 -130 u51.5 +100
Sun (12/17) @ 1:02pm ET ATL Falcons o35 -110 o16.5 +114 o18.5 +135 o32.5 -115 o15.5 -169 o16 +110
CAR Panthers u35 -110 u16.5 -145 u18.5 -175 u32.5 -114 u15.5 +130 u16 -141
Sun (12/17) @ 1:02pm ET NY Jets u40.5 -110 u30.5 -167 u30.5 -1667 u30.5 -130 u30.5 -175
MIA Dolphins o40.5 -110 o30.5 +130 o30.5 +725 o30.5 +100 o30.5 +140
Sun (12/17) @ 1:02pm ET HOU Texans o37.5 -110 o35.5 +154 o29.5 -105 o28.5 +108 o30.5 -112
TEN Titans u37.5 -110 u35.5 -200 u29.5 -125 u28.5 -141 u30.5 -112
Sun (12/17) @ 1:02pm ET CHI Bears o38 -110 o29.5 -145 o34.5 +100 o35.5 -114 o37 -161
CLE Browns u38 -110 u29.5 +114 u34.5 -130 u35.5 -114 u37 +130
Sun (12/17) @ 1:02pm ET TB Buccaneers u42.5 -110 u54.5 -556 u58.5 -120 u54.5 -139 u54.5 -263
GB Packers o42.5 -110 o54.5 +370 o58.5 -110 o54.5 +106 o54.5 +200
Sun (12/17) @ 1:02pm ET NY Giants u36.5 -110 u30.5 -2500 u34.5 -115 u35.5 +104 u30.5 -250
NO Saints o36.5 -110 o30.5 +1200 o34.5 -110 o35.5 -135 o30.5 +190
Sun (12/17) @ 1:03pm ET KC Chiefs o37.5 -110 o50.5 -278 o50.5 +185 o39.5 -110 o39.5 -114 o46.5 -189 o50.5 -294
NE Patriots u37.5 -110 u50.5 +210 u50.5 -250 u39.5 -110 u39.5 -108 u46.5 +142 u50.5 +220
Sun (12/17) @ 4:05pm ET WAS Commanders u48.5 -110 u37.5 -120 u41.5 +120 u49.0 -108 u41.5 +126 u41.5 +120
LA Rams o48.5 -110 o37.5 -110 o41.5 -154 o49.0 -114 o41.5 -167 o41.5 -149
Sun (12/17) @ 4:05pm ET SF 49ers u46.5 -110 u73.5 -105 u68.5 -110 u48.0 -114 u70.5 -120 u67.5 -189
ARI Cardinals o46.5 -110 o73.5 -125 o68.5 -120 o48.0 -108 o70.5 -110 o67.5 +150
Sun (12/17) @ 4:26pm ET DAL Cowboys u48.5 -110 u41.5 -5000 u41.5 -125 u48.5 -104 u41.5 -147 u40.5 0
BUF Bills o48.5 -110 o41.5 +1600 o41.5 -105 o48.5 -127 o41.5 +114 o40.5 0
Sun (12/17) @ 8:22pm ET BAL Ravens o43.5 -110 o35.5 -141 o33.5 -175 o42.5 -109 o33.5 -169 o30.5 0
JAX Jaguars u43.5 -110 u35.5 +110 u33.5 +135 u42.5 -112 u33.5 +130 u30.5 0
Mon (12/18) @ 8:15pm ET PHI Eagles o47.5 -110 o37.5 +210 o31.5 +145 o36.5 -161 o30.5 0
SEA Seahawks u47.5 -110 u37.5 -278 u31.5 -189 u36.5 +122 u30.5 0

NFL Week 15 Odds

Here’s a game-by-game peek at NFL Week 15 betting lines from DraftKings:

Saturday, December 17

Colts at Vikings (-3.5, 47.5)

Some support for Indianapolis here after Minnesota opened at -5. The Vikings can clinch the NFC North with a win over the Colts or a loss by the Lions.

Ravens at Browns (-3, 38)

Lamar Jackson (knee) is out again for the Ravens. Baltimore’s defense has been up to the task lately, giving up an average of just 13. 7 points in their last four games. Baltimore (9-4) is currently tied with Cincinnati atop the AFC North.

Dolphins at Bills (-7, 44)

Miami’s Tyreek Hill (ankle) was a full participant in practice on Wednesday and Thursday, but RB Jeff Wilson Jr. (hip) is questionable heading into this huge AFC East matchup.

Buffalo Bills quarterback Josh Allen (17) celebrates a touchdown pass to wide receiver Stefon Diggs. (AP Photo/Reed Hoffmann)

Miami will be playing its third consecutive road game after losses to the 49ers and Chargers. The Dolphins beat the Bills, 21-19, in Week 3.

Miami is 1-4 ATS as a road dog this season.

Sunday, December 18

Eagles (-9, 48.5) at Bears

Philly backers have bet this up a full three points after the Eagles opened at -6. The Eagles clinched a playoff berth for the fourth time in the last five years with a win against the Giants in Week 14. The Bears (3-10) are officially out of playoff contention.

Cowboys (-4, 48) at Jaguars

Jacksonville took some money during the week after Dallas opened at -6. Interesting trend on the total here: Dallas and Jacksonville have played to the Over the last five times they’ve met. Dallas has won six of its last seven games SU.

Falcons at Saints (-4, 43.5)

The Saints have owned the Falcons, winning five of the last six games in the series. Both teams have been playing to the Under of late.

Lions at Jets (-2, 44.5)

Detroit is 5-0 ATS in its last five games and 5-1 SU in its last six. The Over is 4-1 in the last five games between the Lions and Jets, but bettors favor the Under here after the total opened at 48.

Bengals (-3.5, 44.5) at Bucs

Tampa Bay got exposed in last week’s 35-7 loss at San Francisco. The Bucs have yet to cover at Raymond James Stadium this season. They are 0-5-1 ATS at home.

Titans at Chargers (-3, 46.5)

Tennessee is 5-1 ATS in its last six road games. The Chargers have won their last five games SU against the Titans when playing at home.

Giants at Commanders (-4.5, 40.5)

If it feels like these two teams played fairly recently, it’s because they did. This will be a rematch of the 20-20 tie in Week 13. Washington is 6-1-1 ATS in its last eight games.

Monday, December 19

Rams at Packers (-7, 39.5)

San Francisco’s win over Seattle on TNF helped Green Bay’s slim playoff chances. This looked like a gem of a MNF game at the beginning of the season. The defending Super Bowl champions taking on a perennial playoff team with so much on the line to end Week 15. Unfortunately, for ESPN anyway, this doesn’t qualify as appointment viewing anymore — unless you gamble on it!

The Rest of NFL Week 15 Games

Chiefs (-14, 49.5) at Texans

Steelers at Panthers (-2.5, 37.5)

Cardinals at Broncos (-3, 37)

Patriots at Raiders (-1, 44.5)

Also read: Super Bowl 57 Odds

About the Author
Kris Johnson

Kris Johnson

Senior Writer
Kris Johnson is a senior writer at Gaming Today with more than 15 years of experience as a sports journalist. Johnson's work has appeared in Sports Business Daily, Sports Business Journal, NASCAR Illustrated, and other publications. He also authored a sports betting novel titled The Endgame.

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