NFL Week 5 Odds: Market Continues To Move Toward Bills In AFC Championship Rematch At Chiefs

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The betting line for the Week 5 Bills at Chiefs tilt, a rematch of last season’s AFC Championship Game, has moved steadily toward the road underdog, with Kansas City -2.5 (-120) a prominent number on oddsboards Friday. The Chiefs were -3.5 in advanced wagering last week and opened -3 at most sportsbooks earlier this week. Bills +3 (-114) was available at FanDuel as of this Friday update.

In an important NFC West contest in Week 5, the Cardinals are priced between -4.5 (WynnBet, PointsBet) to -5 (Caesars) for their home date with the 49ers. Arizona was just -2.5 on look-ahead lines last week but earned more believers with a  37-20 win at the Rams last week. The number was as high as Arizona -5.5 at some sportsbooks, including DraftKings and BetRivers, in early wagering.

Other intriguing games on the Week 5 card include a Sunday morning treat from London, and then Packers at Bengals, Browns at Chargers, and Giants at Cowboys on Sunday afternoon.

The Rams covered as 2.5-point favorites in a 26-17 win at Seahawks on Thursday night to kick off the week’s NFL action.

Here’s a look at the NFL Week 5 betting board. Point spreads and totals reflect the market consensus as of Friday.

Live Week 5 Sportsbook Odds

Bet TypeSpreads
Open
Thu (10/7) @ 8:21pm ET LA Rams -110 -500 -500 0 -143 0
SEA Seahawks -105 +340 +360 +3000 +128 0
Sun (10/10) @ 9:30am ET NY Jets +160 +5000 +3300 +3000 +120 +8000 +125
ATL Falcons -189 0 -10000 0 -135 0 -145
Sun (10/10) @ 1:00pm ET PHI Eagles +150 0 +700 -1000 +123 0 0
CAR Panthers -175 +4000 -1250 +625 -139 +5000 0
Sun (10/10) @ 1:00pm ET GB Packers -175 -588 -345 -110 -137 -263 -185
CIN Bengals +150 +385 +250 -120 +120 +210 +155
Sun (10/10) @ 1:00pm ET NE Patriots -500 0 +175 -10000 -357 0 -120
HOU Texans +375 +5000 -250 +2800 +300 +3000 +100
Sun (10/10) @ 1:00pm ET TEN Titans -200 -10000 -5000 0 -196 0 -714
JAX Jaguars +165 +3500 +1400 +6000 +170 +4000 +500
Sun (10/10) @ 1:00pm ET DET Lions +300 -130 +450 +700 +340 0 0
MIN Vikings -370 +100 -667 -1250 -417 0 0
Sun (10/10) @ 1:00pm ET DEN Broncos -105 +850 +1300 +6000 -122 +730 +310
PIT Steelers -110 -1667 -5000 0 +108 -1250 -417
Sun (10/10) @ 1:00pm ET MIA Dolphins +450 +9000 +600 +5000 +430 +8000 0
TB Buccaneers -667 0 -1000 0 -556 0 0
Sun (10/10) @ 1:00pm ET NO Saints -115 0 -400 0 -141 0 0
WAS Washington +100 +10000 +300 +6000 +123 +8000 0
Sun (10/10) @ 4:05pm ET CLE Browns -105 +1800 +825 +900 +116 0 0
LA Chargers -110 -5000 -1667 -1667 -132 0 0
Sun (10/10) @ 4:05pm ET CHI Bears +190 0 -1667 0 +205 0 0
LV Raiders -227 +9000 +900 +5000 -238 +8000 0
Sun (10/10) @ 4:25pm ET SF 49ers +155 +3500 +1200 +2000 +200 +3000 0
ARI Cardinals -189 -10000 -3333 -5000 -233 0 0
Sun (10/10) @ 4:25pm ET NY Giants +300 +9000 +1400 +5000 +251 +8000 +260
DAL Cowboys -370 0 -5000 0 -294 0 -345
Sun (10/10) @ 8:22pm ET BUF Bills +125 -2500 -2000 -1667 +125 -5000 -333
KC Chiefs -149 +1000 +1000 +850 -143 +1300 +260
Mon (10/11) @ 8:15pm ET IND Colts +250 +1000 +240 +270 +275 +790 -417
BAL Ravens -303 -2500 -303 -345 -333 -1429 +310
Thu (10/7) @ 8:21pm ET LA Rams -1.0 -105 -6.5 -110 -8.5 -115 -8.5 -238 -2.5 -114 -5.5 0
SEA Seahawks +1.0 -115 +6.5 -120 +8.5 -105 +8.5 +195 +2.5 +100 +5.5 0
Sun (10/10) @ 9:30am ET NY Jets +4.0 -110 +10.5 -110 +10.5 +110 +7.0 +475 +2.5 +100 +7.5 0 +2.5 +100
ATL Falcons -4.0 -110 -10.5 -120 -10.5 -135 -7.0 -714 -2.5 -114 -7.5 +1200 -2.5 -120
Sun (10/10) @ 1:00pm ET PHI Eagles +3.5 -105 +4.5 +115 +8.5 +100 -5.5 -208 +2.5 -106 -3.5 +132 +12.0 0
CAR Panthers -3.5 -115 -4.5 -145 -8.5 -120 +5.5 +170 -2.5 -115 +3.5 -169 -12.0 0
Sun (10/10) @ 1:00pm ET GB Packers -3.5 -115 -7.5 -125 -4.5 -110 +1.5 -115 -2.5 -114 -2.5 -263 -2.5 -115
CIN Bengals +3.5 -105 +7.5 -105 +4.5 -110 -1.5 -115 +2.5 -108 +2.5 +200 +2.5 -105
Sun (10/10) @ 1:00pm ET NE Patriots -9.5 -110 -1.5 -110 +3.5 -141 -3.0 -208 -8.0 -109 -3.5 +1200 -1.0 -110
HOU Texans +9.5 -110 +1.5 -120 -3.5 +115 +3.0 +170 +8.0 -112 +3.5 0 +1.0 -110
Sun (10/10) @ 1:00pm ET TEN Titans -4.5 -110 -11.5 -110 -20.5 -125 -15.5 +150 -5.0 -109 -12.5 +134 -10.5 -105
JAX Jaguars +4.5 -110 +11.5 -120 +20.5 +105 +15.5 -179 +5.0 -112 +12.5 -172 +10.5 -115
Sun (10/10) @ 1:00pm ET DET Lions +7.5 -110 +4.5 -115 +7.5 -115 +2.0 -500 +10.0 -112 +1.5 +1200 +7.5 0
MIN Vikings -7.5 -110 -4.5 -115 -7.5 -105 -2.0 +375 -10.0 -109 -1.5 0 -7.5 0
Sun (10/10) @ 1:00pm ET DEN Broncos +1.5 -115 +7.5 +185 +10.5 -105 +8.0 -1429 -2.0 -108 +7.5 +210 +8.0 -105
PIT Steelers -1.5 -105 -7.5 -244 -10.5 -115 -8.0 +800 +2.0 -108 -7.5 -278 -8.0 -115
Sun (10/10) @ 1:00pm ET MIA Dolphins +10.5 -110 +28.0 -120 +9.5 +105 +30.5 +140 +11.0 -112 +34.5 +134 +17.5 0
TB Buccaneers -10.5 -110 -28.0 -110 -9.5 -125 -30.5 -169 -11.0 -109 -34.5 -172 -17.5 0
Sun (10/10) @ 1:00pm ET NO Saints -1.5 -105 -8.5 -110 -6.5 -135 -11.0 -208 -2.5 -115 -11.5 +440 +1.5 0
WAS Washington +1.5 -115 +8.5 -120 +6.5 +110 +11.0 +170 +2.5 -106 +11.5 -714 -1.5 0
Sun (10/10) @ 4:05pm ET CLE Browns +1.0 -115 -4.0 -120 -3.5 -125 +4.5 +900 +2.5 -109 +5.5 0 -4.0 0
LA Chargers -1.0 -105 +4.0 -110 +3.5 +105 -4.5 -1667 -2.5 -112 -5.5 +1200 +4.0 0
Sun (10/10) @ 4:05pm ET CHI Bears +5.5 -110 -10.5 -263 -4.5 -120 -11.0 +225 +5.0 -108 -11.5 0 -3.5 0
LV Raiders -5.5 -110 +10.5 +200 +4.5 +100 +11.0 -278 -5.0 -108 +11.5 0 +3.5 0
Sun (10/10) @ 4:25pm ET SF 49ers +3.5 -105 +6.0 -110 +7.5 -110 +7.0 +120 +5.5 -108 +7.5 -3333 +4.5 -115
ARI Cardinals -3.5 -115 -6.0 -120 -7.5 -110 -7.0 -149 -5.5 -114 -7.5 +1000 -4.5 -105
Sun (10/10) @ 4:25pm ET NY Giants +7.5 -110 +14.5 -833 +16.5 +180 +23.5 +300 +7.0 -105 +23.5 0 +14.0 -105
DAL Cowboys -7.5 -110 -14.5 +500 -16.5 -227 -23.5 -400 -7.0 -109 -23.5 0 -14.0 -115
Sun (10/10) @ 8:22pm ET BUF Bills +3.0 -110 -11.5 +150 -11.5 +110 -18.0 +100 +2.5 +100 -17.5 -1111 -6.5 -110
KC Chiefs -3.0 -110 +11.5 -185 +11.5 -135 +18.0 -130 -2.5 -114 +17.5 +600 +6.5 -110
Mon (10/11) @ 8:15pm ET IND Colts +7.0 -110 -7.5 -120 +6.5 -105 +7.0 -110 +7.0 -110 +3.5 -139 -5.5 -110
BAL Ravens -7.0 -110 +7.5 -110 -6.5 -115 -7.0 -110 -7.0 -110 -3.5 +108 +5.5 -110
Thu (10/7) @ 8:21pm ET LA Rams o53.5 -110 o36 -120 o36.5 -115 o53.0 -112 o44 0
SEA Seahawks u53.5 -110 u36 -110 u36.5 -105 u53.0 -109 u44 0
Sun (10/10) @ 9:30am ET NY Jets u43.5 -115 u35.5 -125 u47.5 -3333 u45.5 -110 u45.0 -109 u47.5 0 u45.5 -110
ATL Falcons o43.5 -105 o35.5 -105 o47.5 +1250 o45.5 -110 o45.0 -112 o47.5 +1000 o45.5 -110
Sun (10/10) @ 1:00pm ET PHI Eagles u46.5 -110 u38 -105 u39.5 -110 u46 -110 u46.0 -112 u39.5 -149 u40.5 0
CAR Panthers o46.5 -110 o38 -125 o39.5 -110 o46 -110 o46.0 -109 o39.5 +118 o40.5 0
Sun (10/10) @ 1:00pm ET GB Packers u48.5 -110 u45.5 -115 u48.5 -110 u50 -110 u50.5 -108 u47.5 -1111 u54.5 -115
CIN Bengals o48.5 -110 o45.5 -115 o48.5 -110 o50 -110 o50.5 -114 o47.5 +600 o54.5 -105
Sun (10/10) @ 1:00pm ET NE Patriots u39.5 -110 u50.5 -115 u49.5 +100 u39 -110 u39.0 -109 u47.5 0 u45 -115
HOU Texans o39.5 -110 o50.5 -115 o49.5 -120 o39 -110 o39.0 -112 o47.5 +1000 o45 -105
Sun (10/10) @ 1:00pm ET TEN Titans u49.5 -110 u57.5 -115 u62.5 -110 u48.5 -110 u48.5 -108 u50.5 -139 u61.5 -110
JAX Jaguars o49.5 -110 o57.5 -115 o62.5 -110 o48.5 -110 o48.5 -114 o50.5 +108 o61.5 -110
Sun (10/10) @ 1:00pm ET DET Lions o49.5 -110 o29 +100 o31.5 +100 o49.5 -110 o49.5 -109 o36.5 +1000 o41.5 0
MIN Vikings u49.5 -110 u29 -130 u31.5 -120 u49.5 -110 u49.5 -112 u36.5 0 u41.5 0
Sun (10/10) @ 1:00pm ET DEN Broncos o40.5 -110 o46.5 -110 o35.5 -110 o40 -110 o39.5 -109 o46.5 +200 o43 -105
PIT Steelers u40.5 -110 u46.5 -120 u35.5 -110 u40 -110 u39.5 -112 u46.5 -263 u43 -115
Sun (10/10) @ 1:00pm ET MIA Dolphins o49.5 -110 o69 -115 o58.5 +100 o48 -110 o48.0 -108 o68.5 -294 o61.5 0
TB Buccaneers u49.5 -110 u69 -115 u58.5 -120 u48 -110 u48.0 -114 u68.5 +215 u61.5 0
Sun (10/10) @ 1:00pm ET NO Saints o43.5 -110 o53 -115 o52.5 -115 o43.5 -110 o43.5 -108 o55.5 +300 o49 0
WAS Washington u43.5 -110 u53 -115 u52.5 -105 u43.5 -110 u43.5 -114 u55.5 -435 u49 0
Sun (10/10) @ 4:05pm ET CLE Browns o49.5 -110 o74 -115 o73.5 -105 o47 -110 o47.0 -110 o89.5 +1000 o73 0
LA Chargers u49.5 -110 u74 -115 u73.5 -115 u47 -110 u47.0 -110 u89.5 0 u73 0
Sun (10/10) @ 4:05pm ET CHI Bears o45.5 -110 o30 -110 o30.5 -115 o46 -110 o46.0 -108 o29.5 +1000 o31.5 0
LV Raiders u45.5 -110 u30 -120 u30.5 -105 u46 -110 u46.0 -114 u29.5 0 u31.5 0
Sun (10/10) @ 4:25pm ET SF 49ers u53.5 -115 u24.5 -125 u25.5 -115 u48.5 -110 u48.5 -112 u27.5 -1111 u29.5 -105
ARI Cardinals o53.5 -105 o24.5 -105 o25.5 -105 o48.5 -110 o48.5 -109 o27.5 +600 o29.5 -115
Sun (10/10) @ 4:25pm ET NY Giants u49.5 -110 u52.5 -110 u48.5 +110 u52.5 -110 u52.5 -112 u64.5 -5000 u54.5 -115
DAL Cowboys o49.5 -110 o52.5 -120 o48.5 -135 o52.5 -110 o52.5 -109 o64.5 +1000 o54.5 -105
Sun (10/10) @ 8:22pm ET BUF Bills o56.5 -110 o61.5 -115 o61.5 +105 o56.5 -110 o58.5 +430 o65.5 -110
KC Chiefs u56.5 -110 u61.5 -115 u61.5 -125 u56.5 -110 u58.5 -667 u65.5 -110
Mon (10/11) @ 8:15pm ET IND Colts u48.5 -110 u48.5 -115 u46.5 -110 u46 -110 u46.0 -110 u55.5 +180 u50.5 -105
BAL Ravens o48.5 -110 o48.5 -115 o46.5 -110 o46 -110 o46.0 -110 o55.5 -233 o50.5 -115

NFL Week 5 Lines & Early Moves

Point spreads, totals, and early adjustments for this week’s NFL betting action.

Jets vs. Falcons (-3 even, 45.5)

A significant market move toward the Jets for this game in London that kicks off at 9:30 am ET, just in time for some breakfast betting, as the Falcons opened -3.5 and are down to -2.5 (-120) at several shops. Atlanta will be without wide receivers Calvin Ridley and Justin Gage.

Eagles at Panthers (-3, 44.5)

It’s been dog and UNDER money for this pairing of NFC hopefuls, which opened Carolina -4 and 46.

Packers (-3 even, 50.5) at Bengals

In this inter-conference battle of 3-1 teams, the hook drew some attention from bettors who grabbed Cincy +3.5 early. The line, in fact, sits -2.5 (-120) in some spots. The total has been pushed up from 49.

Patriots (-9, 39.5) at Texans

One of the largest spreads of the week comes with the lowest total, a dynamic that — despite Houston’s ineptitude — may have caught the eye of underdog bettors, as 9.5s and have become 8.5s on some oddsboards.

Titans (-4.5, 48.5) at Jaguars

SuperBook USA opened Tennessee -3.5 on Sunday night, a massive adjustment from the shop’s look-ahead line of -7.5. The Titans were without their two best wide receivers when they lost as 5.5-point favorites at the Jets in overtime in Week 4, 27-24. Jacksonville is one of two winless teams remaining in the league but was game in 24-21 loss at the Bengals on Thursday.

Lions at Vikings (-10, 49.5)

A large spread has become larger as bettors fade the NFL’s other winless team, the Lions, pushing the line up from 8.5.

Broncos (-1, 39.5) at Steelers

After early sentiment on Pittsburgh moved the line to Pitt -1 from a pick ‘em opener, the favorite has flipped. Broncos QB Teddy Bridgewater is expected to start after being cleared from concussion protocol.

Dolphins at Bucs (-10, 48)

Dog bettors grabbed Dolphins +10.5 early, and UNDER money has also shown up ahead of the weekend. The Bucs continue to command large point spreads, but they haven’t been covering many of them, falling to 1-3 ATS with their narrow 19-17 win as touchdown favorites in New England on Sunday night.

Saints (-2.5, 43.5) at Washington

Books have written some action on Saints -1, as the line sits between -2 and -2.5 Friday. The total has seen a downward adjustment from 44.

Browns at Chargers (-2, 47)

Early action has been on the Chargers in the matchup of AFC contenders, which opened pick ’em. Contestants competing in Bookies Battle are on board with their customers, as Los Angeles is the most popular pick of this season’s contest so far.

Bears at Raiders (-5.5, 44.5)

Small move on the Raiders, who opened -5, and UNDER, which opened 45.

49ers at Cardinals (-4.5, 50.5)

The bigger move on this game has come on the total, as it’s been bet down from 53.5.

Giants at Cowboys (-7, 52)

Despite another impressive showing by Dallas in a 36-28 win over the Panthers, this line tightened from a -8.5 look-ahead number and from a -7.5 opener. OVER love has pushed the total up from 50.5.

Bills at Chiefs (-3, 56.5)

If this total sticks, it will be the highest of the season so far. OVER 55 cashed in Kansas City’s 38-24 playoff win over Buffalo last January.

Colts at Ravens (-7, 47.5)

WynnBET goes Baltimore -6.5 for the Week 5 Monday nighter, which sees the Colts look for their second win of the season as they visit their former hometown.

Check out updated Super Bowl odds 2022.

About the Author

Marcus DiNitto

Marcus DiNitto is a nationally recognized editor and writer specializing in sports betting and sports business. He is the editor for Louisiana Sharp. He has been managing editor at SportsBusiness Daily, USA Sports Gaming, Sporting News and The Linemakers. Marcus earned his MBA from the University of North Carolina-Charlotte.

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