NFL Week 6 Odds: Cowboys-Eagles Betting Line Moves in Philly’s Favor

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Two huge tilts headline the NFL Week 6 slate, and we’re here to examine updated odds and betting line movements.

The Buffalo Bills remain a short road favorite vs. the Kansas City Chiefs in this week’s marquee matchup. The undefeated Philadelphia Eagles have been bet up and are laying a big number at home to the Dallas Cowboys in a battle for NFC East supremacy.

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NFL Week 6 Betting Lines: Updated Point Spreads, Totals, Moneylines

Here are updated Week 6 lines that can be found on sportsbook apps around the US.

Bet TypeSpreads
Open
Thu (10/12) @ 8:18pm ET DEN Broncos +400 +3000 +3300 +4500 +3000 +15000
KC Chiefs -556 0 -10000 0 0 -10000
Sun (10/15) @ 9:33am ET BAL Ravens -200 -3333 -10000 0 -263 0 0
TEN Titans +165 +1400 +3300 +4000 +200 +2500 +4500
Sun (10/15) @ 1:03pm ET WAS Commanders +110 -2000 -2000 -1250 +105 -5000 -2000
ATL Falcons -130 +1000 +900 +700 -130 +1100 +900
Sun (10/15) @ 1:03pm ET MIN Vikings -185 -588 -10000 0 -164 -5000 -10000
CHI Bears +150 +390 +3300 +4000 +135 +1200 +2000
Sun (10/15) @ 1:03pm ET SEA Seahawks +120 +290 +300 +850 +125 +285 +300
CIN Bengals -145 -417 -500 -1667 -152 -400 -417
Sun (10/15) @ 1:03pm ET SF 49ers -208 -833 -588 -909 -526 -185 -588
CLE Browns +170 +520 +400 +550 +390 +142 +375
Sun (10/15) @ 1:03pm ET NO Saints -130 +800 +800 +320 -141 +750 +6000
HOU Texans +110 -1667 -1667 -455 +118 -1667 0
Sun (10/15) @ 1:03pm ET IND Colts +180 +3000 +3300 +3000 +165 +2500 +2800
JAX Jaguars -227 0 -10000 0 -200 0 -10000
Sun (10/15) @ 1:03pm ET CAR Panthers +600 +2500 +3300 +850 +650 +3000 0
MIA Dolphins -909 -10000 -10000 -1667 -1111 0 0
Sun (10/15) @ 4:06pm ET NE Patriots +130 +420 +800 +4000 +125 +430 0
LV Raiders -154 -667 -2000 0 -149 -667 0
Sun (10/15) @ 4:25pm ET PHI Eagles -278 +380 +1400 +260 -303 +450 +250
NY Jets +225 -588 -10000 -345 +235 -769 -556
Sun (10/15) @ 4:25pm ET ARI Cardinals +225 +1200 +950 +900 +245 +1200 +4000
LA Rams -278 -2500 -2500 -2000 -313 -5000 0
Sun (10/15) @ 4:26pm ET DET Lions -175 -10000 -10000 -5000 -164 -10000 -10000
TB Buccaneers +145 +2000 +3300 +1400 +135 +1700 +3000
Sun (10/15) @ 8:23pm ET NY Giants +600 -115 -130 -105 +800 +108 +800
BUF Bills -909 -115 +100 -125 -1429 -139 -1429
Mon (10/16) @ 8:16pm ET DAL Cowboys -130 -357 -455 -149 -172 -189
LA Chargers +110 +260 +300 +120 +134 +125
Thu (10/12) @ 8:18pm ET DEN Broncos +10.5 -110 +10.5 +420 +10.5 +400 +11.0 +400 +10.5 +330 +11.0 -417
KC Chiefs -10.5 -110 -10.5 -667 -10.5 -667 -11.0 -588 -10.5 -500 -11.0 +310
Sun (10/15) @ 9:33am ET BAL Ravens -3.5 -115 -7.5 0 -10.5 -278 -8.0 -1000 -5.5 -108 -10.5 -227 -10.5 -208
TEN Titans +3.5 -105 +7.5 +3500 +10.5 +200 +8.0 +600 +5.5 -114 +10.5 +168 +10.5 +165
Sun (10/15) @ 1:03pm ET WAS Commanders +2.5 -115 -7.5 -278 -8.5 -164 -7.5 -278 +1.5 -110 -8.5 +198 -8.0 +175
ATL Falcons -2.5 -105 +7.5 +210 +8.5 +125 +7.5 +215 -1.5 -110 +8.5 -270 +8.0 -227
Sun (10/15) @ 1:03pm ET MIN Vikings -3.5 -110 -6.5 +1300 -6.5 +240 -5.5 -189 -3.0 -110 -5.5 -270 -6.0 +160
CHI Bears +3.5 -110 +6.5 -3333 +6.5 -345 +5.5 +150 +3.0 -110 +5.5 +198 +6.0 -200
Sun (10/15) @ 1:03pm ET SEA Seahawks +2.5 -105 +3.5 +140 +3.5 +140 +4.5 -179 +2.5 -104 +3.5 +165 +3.5 +120
CIN Bengals -2.5 -115 -3.5 -179 -3.5 -185 -4.5 +145 -2.5 -118 -3.5 -222 -3.5 -149
Sun (10/15) @ 1:03pm ET SF 49ers -4.5 -110 +2.5 -149 +2.5 -10000 -1.5 -110 -14.5 +160 -1.5 +100 -3.0 -112
CLE Browns +4.5 -110 -2.5 +120 -2.5 +3300 +1.5 -120 +14.5 -204 +1.5 -130 +3.0 -112
Sun (10/15) @ 1:03pm ET NO Saints -2.5 -110 +6.5 +230 +6.5 +250 +7.0 -238 -2.0 -114 +6.5 +265 +4.0 -105
HOU Texans +2.5 -110 -6.5 -313 -6.5 -345 -7.0 +185 +2.0 -108 -6.5 -385 -4.0 -120
Sun (10/15) @ 1:03pm ET IND Colts +4.5 -110 +16.5 +450 +15.5 +950 +17.0 +145 +3.5 -104 +16.5 +285 +17.0 +450
JAX Jaguars -4.5 -110 -16.5 -714 -15.5 -3333 -17.0 -179 -3.5 -118 -16.5 -417 -17.0 -714
Sun (10/15) @ 1:03pm ET CAR Panthers +14.0 -110 +20.5 +470 +20.5 +2200 +23.5 +100 +14.0 -112 +20.5 +375 +21.0 0
MIA Dolphins -14.0 -110 -20.5 -769 -20.5 -10000 -23.5 -130 -14.0 -118 -20.5 -588 -21.0 0
Sun (10/15) @ 4:06pm ET NE Patriots +2.5 -110 +4.5 -110 +3.5 -120 +2.5 -115 +3.0 -114 +2.5 -135 +2.5 -112
LV Raiders -2.5 -110 -4.5 -120 -3.5 -110 -2.5 -115 -3.0 -108 -2.5 +104 -2.5 -112
Sun (10/15) @ 4:25pm ET PHI Eagles -6.0 -110 -1.5 -179 -2.5 +140 -1.5 -189 -6.5 -110 -1.5 -222 -3.0 -112
NY Jets +6.0 -110 +1.5 +140 +2.5 -185 +1.5 +150 +6.5 -110 +1.5 +165 +3.0 -112
Sun (10/15) @ 4:25pm ET ARI Cardinals +6.0 -110 +16.5 +350 +16.5 +550 +17.0 -1250 +7.0 -110 +16.5 +940 +17.0 0
LA Rams -6.0 -110 -16.5 -526 -16.5 -1000 -17.0 +670 -7.0 -110 -16.5 -3333 -17.0 0
Sun (10/15) @ 4:26pm ET DET Lions -3.0 -120 -13.5 -278 -13.5 -161 -14.0 -278 -3.0 -109 -13.5 -213 -14.0 -227
TB Buccaneers +3.0 +100 +13.5 +210 +13.5 +125 +14.0 +215 +3.0 -112 +13.5 +162 +14.0 +175
Sun (10/15) @ 8:23pm ET NY Giants +14.5 -110 +5.5 -345 +5.5 -200 +5.5 -400 +15.5 -109 +3.5 -118 +5.0 +190
BUF Bills -14.5 -110 -5.5 +250 -5.5 +150 -5.5 +290 -15.5 -112 -3.5 -110 -5.0 -250
Mon (10/16) @ 8:16pm ET DAL Cowboys -2.0 -110 -3.5 +210 -3.5 +145 -2.5 -135 -3.5 +225 -3.5 +150
LA Chargers +2.0 -110 +3.5 -278 +3.5 -189 +2.5 +105 +3.5 -313 +3.5 -189
Thu (10/12) @ 8:18pm ET DEN Broncos o51.5 -110 o23.5 -130 o23.5 -125 o23.5 -120 o27 -149
KC Chiefs u51.5 -110 u23.5 +100 u23.5 -105 u23.5 -108 u27 +120
Sun (10/15) @ 9:33am ET BAL Ravens o40.5 -110 o37.5 +190 o37.5 +170 o42 -110 o42.0 -110 o39.5 -135 o37.5 +145
TEN Titans u40.5 -110 u37.5 -250 u37.5 -227 u42 -110 u42.0 -110 u39.5 +104 u37.5 -179
Sun (10/15) @ 1:03pm ET WAS Commanders u42.5 -115 u48.5 -115 u44.5 -120 u42 -110 u42.0 -112 u47.5 -120 u40.5 -161
ATL Falcons o42.5 -105 o48.5 -115 o44.5 -110 o42 -110 o42.0 -109 o47.5 -108 o40.5 +130
Sun (10/15) @ 1:03pm ET MIN Vikings u49.5 -115 u34.5 +114 u32.5 -149 u45 -110 u44.5 -112 u35.5 -139 u35 +100
CHI Bears o49.5 -105 o34.5 -145 o32.5 +115 o45 -110 o44.5 -109 o35.5 +106 o35 -125
Sun (10/15) @ 1:03pm ET SEA Seahawks u46.5 -115 u36.5 +114 u36.5 +115 u45.5 -110 u45.5 -112 u36.5 +128 u36.5 +110
CIN Bengals o46.5 -105 o36.5 -145 o36.5 -149 o45.5 -110 o45.5 -109 o36.5 -167 o36.5 -141
Sun (10/15) @ 1:03pm ET SF 49ers u42 -110 u36.5 -120 u38.5 -10000 u36 -110 u31.5 +155 u36.5 +100 u37 +110
CLE Browns o42 -110 o36.5 -110 o38.5 +3300 o36 -110 o31.5 -204 o36.5 -130 o37 -141
Sun (10/15) @ 1:03pm ET NO Saints u40.5 -105 u33.5 -208 u33.5 -145 u42 -110 u47.0 -227 u33.5 -222 u42.5 +105
HOU Texans o40.5 -115 o33.5 +160 o33.5 +110 o42 -110 o47.0 +165 o33.5 +165 o42.5 -130
Sun (10/15) @ 1:03pm ET IND Colts o45.5 -110 o57.5 +420 o58.5 +675 o44 -110 o44.5 -103 o57.5 +102 o54.5 +105
JAX Jaguars u45.5 -110 u57.5 -667 u58.5 -1429 u44 -110 u44.5 -120 u57.5 -132 u54.5 -130
Sun (10/15) @ 1:03pm ET CAR Panthers o47.5 -115 o54.5 -115 o56.5 +135 o47.5 -110 o47.0 -118 o51.5 -120 o63.5 0
MIA Dolphins u47.5 -105 u54.5 -115 u56.5 -175 u47.5 -110 u47.0 -112 u51.5 -108 u63.5 0
Sun (10/15) @ 4:06pm ET NE Patriots u42.5 -110 u36.5 -167 u35.5 +135 u41.5 -110 u41.5 -112 u36.5 -222 u36 -149
LV Raiders o42.5 -110 o36.5 +130 o35.5 -175 o41.5 -110 o41.5 -109 o36.5 +165 o36 +120
Sun (10/15) @ 4:25pm ET PHI Eagles u42.5 -110 u31.5 +105 u31.5 -105 u43.5 -110 u31.5 +104 u32.5 -125
NY Jets o42.5 -110 o31.5 -135 o31.5 -125 o43.5 -110 o31.5 -135 o32.5 +100
Sun (10/15) @ 4:25pm ET ARI Cardinals o46.5 -110 o38.5 -141 o37.5 -110 o47.5 -109 o35.5 +100 o35.5 0
LA Rams u46.5 -110 u38.5 +110 u37.5 -115 u47.5 -112 u35.5 -130 u35.5 0
Sun (10/15) @ 4:26pm ET DET Lions o45.5 -110 o36.5 -105 o28.5 -141 o43.0 -110 o36.5 -108 o32.5 -125
TB Buccaneers u45.5 -110 u36.5 -125 u28.5 +105 u43.0 -110 u36.5 -120 u32.5 +100
Sun (10/15) @ 8:23pm ET NY Giants u46.5 -110 u23.5 -105 u23.5 -105 u43.5 -112 u23.5 -106 u24.5 -370
BUF Bills o46.5 -110 o23.5 -125 o23.5 -125 o43.5 -109 o23.5 -122 o24.5 +280
Mon (10/16) @ 8:16pm ET DAL Cowboys o47.5 -110 o40.5 -130 o40.5 -145 o40.5 -147 o40.5 -120
LA Chargers u47.5 -110 u40.5 +100 u40.5 +110 u40.5 +112 u40.5 -105

Betting lines below are via DraftKings as of Friday morning.

San Francisco 49ers (-5, 44.5) at Atlanta Falcons

Slight move in Atlanta’s direction here after this game opened at 49ers -6. The Falcons are the only team in the NFL with a 5-0 ATS record. Keep an eye on the total here as it’s been bet up from 42.5. The under has cashed in seven of San Francisco’s last eight games.

New England Patriots at Cleveland Browns (-2.5, 43)

The Pats are 7-2 ATS in their last nine games against the Browns. Starting QB Mac Jones (ankle) was a limited participant in practice on Thursday. There’s a good chance that rookie Bailey Zappe will be under center again vs. the Browns. Zappe led New England to a 29-0 win over Detroit last week.

New York Jets at Green Bay Packers (-7.5, 45)

We included the Packers in our NFL Week 6 teaser and fully expect Green Bay to cover the adjusted -1.5 spread. But the Jets look like the right choice getting a TD and the hook here. New York is 4-1 ATS in its last five road games.

Jacksonville Jaguars at Indianapolis Colts (-2, 42)

It’s fun to look back and laugh sometimes. DraftKings was dealing the Colts -7 over the summer for this AFC South matchup. Fast forward to today and Indy is last in the league in scoring (13. 8 points per game) through Week 5. The Jags have covered their last five games against the Colts.

Minnesota Vikings (-3.5, 45.5) vs. Miami Dolphins

Miami has been a cover machine at home, going 7-1 ATS in its last eight as the host team. Will that change with third-string QB Skylar Thompson making his first career start against the Vikings?

Cincinnati Bengals (-2.5, 43) at New Orleans Saints

Cincy money has moved this from an opener of Bengals -1. It’s about time for the Bengals to put up some points. Cincinnati games have gone 5-0 to the Under this season.

Baltimore Ravens at New York Giants (-5.5, 45.5)

The Giants are typically involved in low-scoring games at home. They’ve gone Under in seven of the last eight at MetLife Stadium. But this total has been bet up a full two points from the opener. 

Tampa Bay Bucs at Pittsburgh Steelers (-8.5, 45.5)

Mike Tomlin has never had a losing season as head coach of the Steelers…yet. Tampa Bay’s defense could give rookie QB Kenny Pickett fits here. This game looks like an Under waiting to happen. Unders are 48-32 on the year and hitting at a 60% clip.

Carolina Panthers at Los Angeles Rams (-10, 41.5)

The hellscape that is Carolina Panthers football can’t get any worse. Or can it? P.J. Walker will get the start against the Rams, who are having some problems of their own in the wake of last season’s Super Bowl win.

Arizona Cardinals at Seattle Seahawks (-2, 50.5)

Some love for the home dog here after Arizona opened as a three-point favorite. DraftKings was dealing Seattle at +115 on the moneyline as of Friday.

Buffalo Bills (-2.5, 54) at Kansas City Chiefs

The Bills find themselves in the unfamiliar role of favorite against the Chiefs. You saw that stat about Patrick Mahomes in the role of underdog, right? Mahomes is 7-0-1 ATS in his career when the Chiefs are getting points.

It was about this time last year when Buffalo went into Kansas City and rolled, 38-20.

Eagles QB Jalen Hurts (AP Photo/Michael Ainsworth)

Dallas Cowboys at Philadelphia Eagles (-6.5, 42)

Eagles backers have moved this from an opener of Philly -5. This seems like a lot of points to give Dallas, which is 5-0 ATS in its last five road tilts.

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Denver Broncos at Los Angeles Chargers (-4.5, 45.5)

Fun fact: The Under has cashed in eight of the last nine games between these teams when Los Angeles is playing at home. Given Denver’s struggles on the offensive side of the ball and its relative strength on defense, the Under looks like the right play on MNF. 

Also read: NFL Week 6 Betting Strategies | Super Bowl 57 Odds | Cowboys vs. Eagles Odds and Prediction

About the Author
Kris Johnson

Kris Johnson

Senior Writer
Kris Johnson is a senior writer at Gaming Today with more than 15 years of experience as a sports journalist. Johnson's work has appeared in Sports Business Daily, Sports Business Journal, NASCAR Illustrated, and other publications. He also authored a sports betting novel titled The Endgame.

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