NFL Week 7 Betting Odds: 49ers Remain Short Home Dog vs. Chiefs

GamingToday.com is an independent sports news and information service. GamingToday.com has partnerships with some of the top legal and licensed sportsbook companies in the US. Gaming Today may receive referral compensation from the sportsbook company when you claim a bonus offer or promotion through a link on this site. Although the relationships we have with sportsbook companies may influence the order in which we place companies on the site, all reviews, recommendations, and opinions are wholly our own. They are the recommendations from our authors and contributors who are avid sports fans themselves.

For more information, please read How We Rate Sportsbooks, Privacy Policy, or Contact Us with any concerns you may have.

Gaming Today is licensed and regulated to operate in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, ME, MI, MS, NJ, NV, NY, OH, ON, PA, TN, VA, VT, WV, and WY.

Sunday’s Super Bowl 54 rematch between the Kansas City Chiefs and San Francisco 49ers got a little more interesting after the 49ers traded for Carolina RB Christian McCaffrey on Thursday.

DraftKings opened with Kansas City -2.5 earlier this week, but the line had dropped to -2 as of Friday morning. San Francisco remains a short home dog, and the 49ers are 2-0 ATS at Levi’s Stadium.

The following teams have a bye in Week 7: Bills, Rams, Vikings, and Eagles. 

DraftKings Sportsbook

Get $50 NFL Free Bet, $1,000 Deposit Bonus at DraftKings

New users get a $50 free bet, and up to $1,000 deposit bonus at DraftKings.

NFL Week 7 Odds

Bet TypeSpreads
Open
Thu (10/19) @ 8:16pm ET JAX Jaguars -110 -417 -833 0 +120 -357 -417
NO Saints -110 +290 +500 +1000 -147 +260 +280
Sun (10/22) @ 1:01pm ET WAS Commanders -125 +3000 +3300 +195 -159 +172 0
NY Giants +105 0 -10000 -250 +132 -227 0
Sun (10/22) @ 1:02pm ET LV Raiders -161 +1800 +3300 +850 +1200 +6000
CHI Bears +135 -5000 -10000 -1667 -5000 0
Sun (10/22) @ 1:03pm ET DET Lions +115 +3000 +3300 +1200 +1500 +6000
BAL Ravens -141 0 -10000 -5000 -10000 0
Sun (10/22) @ 1:03pm ET ATL Falcons +115 -625 -588 -833 +125 -909 -909
TB Buccaneers -141 +400 +400 +500 -152 +520 +425
Sun (10/22) @ 1:05pm ET CLE Browns -135 0 -10000 -105 -185 -3333 -149
IND Colts +110 +3500 +3300 -125 +150 +1060 +115
Sun (10/22) @ 1:05pm ET BUF Bills -400 +3000 +3000 +5000 -400 +4000 +2000
NE Patriots +325 0 -5000 0 +310 0 0
Sun (10/22) @ 4:06pm ET PIT Steelers +145 0 -10000 -5000 +140 -526 -10000
LA Rams -175 +4000 +1600 +1400 -175 +360 +3000
Sun (10/22) @ 4:06pm ET ARI Cardinals +290 +950 +950 +5000 +350 +1060 +5000
SEA Seahawks -370 -2000 -2500 0 -455 -3333 0
Sun (10/22) @ 4:26pm ET GB Packers -120 +4000 +1000 +6000 +100 +1400 0
DEN Broncos +100 0 -3333 0 -120 -5000 0
Sun (10/22) @ 4:26pm ET LA Chargers +200 +1400 +3300 +700 +195 +1200 +1500
KC Chiefs -250 -3333 -10000 -1250 -244 -5000 -5000
Sun (10/22) @ 8:23pm ET MIA Dolphins +115 +2500 +3300 +1400 +1400 +1800
PHI Eagles -141 -10000 -10000 -5000 -5000 -10000
Mon (10/23) @ 8:16pm ET SF 49ers -303 +175 +333 +850 -313 +255 +130
MIN Vikings +240 -233 -455 -1667 +250 -345 -175
Thu (10/19) @ 8:16pm ET JAX Jaguars -1.5 -105 +1.5 -125 -1.5 -105 -2.5 -135 +2.5 -110 -2.5 -114 -6.5 -278
NO Saints +1.5 -115 -1.5 -105 +1.5 -125 +2.5 +105 -2.5 -110 +2.5 -114 +6.5 +210
Sun (10/22) @ 1:01pm ET WAS Commanders -1.5 -115 +3.5 +105 +4.5 -120 +6.5 +100 -3.0 -112 +4.5 -130 +3.5 -112
NY Giants +1.5 -105 -3.5 -135 -4.5 -110 -6.5 -130 +3.0 -109 -4.5 +100 -3.5 -112
Sun (10/22) @ 1:02pm ET LV Raiders -3.0 -110 +23.5 +360 +23.5 +350 +23.5 +230 +24.5 -278 +24.0 -278
CHI Bears +3.0 -110 -23.5 -526 -23.5 -556 -23.5 -303 -24.5 +205 -24.0 +210
Sun (10/22) @ 1:03pm ET DET Lions +2.5 -110 +31.5 +470 +31.5 +750 +31.5 +165 +31.5 +182 +31.5 +220
BAL Ravens -2.5 -110 -31.5 -769 -31.5 -1667 -31.5 -208 -31.5 -244 -31.5 -294
Sun (10/22) @ 1:03pm ET ATL Falcons +2.5 -110 -2.5 -500 -2.5 -400 -2.5 -345 +2.5 -104 -2.5 -500 -2.5 -323
TB Buccaneers -2.5 -110 +2.5 +340 +2.5 +280 +2.5 +260 -2.5 -118 +2.5 +325 +2.5 +240
Sun (10/22) @ 1:05pm ET CLE Browns -1.5 -115 +4.5 +250 +4.5 +270 -2.5 +110 -3.5 -104 +4.5 +225 +5.0 -263
IND Colts +1.5 -105 -4.5 -345 -4.5 -370 +2.5 -141 +3.5 -118 -4.5 -313 -5.0 +200
Sun (10/22) @ 1:05pm ET BUF Bills -8.5 -105 -1.5 +140 +5.5 -154 +5.5 -110 -7.5 -110 +5.5 -222 +5.5 -112
NE Patriots +8.5 -115 +1.5 -179 -5.5 +120 -5.5 -120 +7.5 -110 -5.5 +165 -5.5 -112
Sun (10/22) @ 4:06pm ET PIT Steelers +3.5 -115 -7.5 +470 -4.5 -125 -6.5 -110 +3.5 -114 -5.5 -125 -7.5 +310
LA Rams -3.5 -105 +7.5 -769 +4.5 -105 +6.5 -120 -3.5 -106 +5.5 -104 +7.5 -417
Sun (10/22) @ 4:06pm ET ARI Cardinals +8.0 -110 +9.5 -115 +9.5 +3300 +11.0 -5000 +9.0 -110 +8.5 +192 +7.0 +105
SEA Seahawks -8.0 -110 -9.5 -115 -9.5 -10000 -11.0 +1800 -9.0 -110 -8.5 -263 -7.0 -130
Sun (10/22) @ 4:26pm ET GB Packers -1.5 -105 +1.5 -179 +1.5 -110 +5.5 -110 +1.5 -110 +1.5 -161 -1.0 +115
DEN Broncos +1.5 -115 -1.5 +140 -1.5 -115 -5.5 -120 -1.5 -110 -1.5 +122 +1.0 -145
Sun (10/22) @ 4:26pm ET LA Chargers +5.5 -110 +13.5 +170 +8.5 -115 +13.5 +260 +5.5 -108 +13.5 +265 +13.5 +230
KC Chiefs -5.5 -110 -13.5 -222 -8.5 -110 -13.5 -345 -5.5 -114 -13.5 -385 -13.5 -303
Sun (10/22) @ 8:23pm ET MIA Dolphins +2.5 -110 +16.5 -115 +14.5 +100 +14.0 +450 +14.5 -164 +14.5 0
PHI Eagles -2.5 -110 -16.5 -115 -14.5 -125 -14.0 -714 -14.5 +126 -14.5 0
Mon (10/23) @ 8:16pm ET SF 49ers -7.0 -110 +4.5 +280 +4.5 +3300 +4.5 +290 -6.5 -114 +3.5 -120 +5.0 -370
MIN Vikings +7.0 -110 -4.5 -400 -4.5 -10000 -4.5 -400 +6.5 -108 -3.5 -108 -5.0 +280
Thu (10/19) @ 8:16pm ET JAX Jaguars o42.5 -110 o58.5 -105 o53.5 -115 o41.5 -110 o41.5 -110 o54.5 -122 o55.5 +120
NO Saints u42.5 -110 u58.5 -125 u53.5 -110 u41.5 -110 u41.5 -110 u54.5 -106 u55.5 -149
Sun (10/22) @ 1:01pm ET WAS Commanders u41.5 -115 u27.5 -125 u28.5 -149 u37 -110 u37.0 -106 u27.5 -114 u27.5 -120
NY Giants o41.5 -105 o27.5 -105 o28.5 +115 o37 -110 o37.0 -115 o27.5 -114 o27.5 -105
Sun (10/22) @ 1:02pm ET LV Raiders u40.5 -110 u33.5 -130 u36.5 -208 u33.5 -125 u37.5 -500
CHI Bears o40.5 -110 o33.5 +100 o36.5 +155 o33.5 -104 o37.5 +350
Sun (10/22) @ 1:03pm ET DET Lions u44.5 -110 u50.5 +130 u50.5 +250 u51.5 -118 u44.5 -263
BAL Ravens o44.5 -110 o50.5 -167 o50.5 -345 o51.5 -110 o44.5 +200
Sun (10/22) @ 1:03pm ET ATL Falcons o39.5 -110 o23.5 +154 o32.5 -125 o37.5 -108 o32.5 -161 o23.5 +125
TB Buccaneers u39.5 -110 u23.5 -200 u32.5 -105 u37.5 -114 u32.5 +122 u23.5 -154
Sun (10/22) @ 1:05pm ET CLE Browns o39.5 -110 o71.5 +165 o68.5 -110 o40 -110 o40.0 -109 o68.5 -104 o71.5 +165
IND Colts u39.5 -110 u71.5 -213 u68.5 -120 u40 -110 u40.0 -112 u68.5 -125 u71.5 -208
Sun (10/22) @ 1:05pm ET BUF Bills o42.5 -110 o46.5 -115 o39.5 +105 o41 -110 o41.0 -110 o39.5 +148 o39 -130
NE Patriots u42.5 -110 u46.5 -115 u39.5 -141 u41 -110 u41.0 -110 u39.5 -196 u39 +105
Sun (10/22) @ 4:06pm ET PIT Steelers u42.5 -110 u48.5 -125 u48.5 -125 u44 -110 u43.5 -110 u48.5 -118 u41.5 -323
LA Rams o42.5 -110 o48.5 -105 o48.5 -105 o44 -110 o43.5 -110 o48.5 -110 o41.5 +240
Sun (10/22) @ 4:06pm ET ARI Cardinals o46.5 -105 o27.5 +120 o37.5 -110 o43.5 -110 o44.0 -108 o27.5 +125 o27.5 +100
SEA Seahawks u46.5 -115 u27.5 -149 u37.5 -115 u43.5 -110 u44.0 -114 u27.5 -164 u27.5 -125
Sun (10/22) @ 4:26pm ET GB Packers u44.5 -110 u38.5 +100 u38.5 +105 u44 -110 u44.0 -108 u38.5 +106 u37.5 -112
DEN Broncos o44.5 -110 o38.5 -130 o38.5 -141 o44 -110 o44.0 -114 o38.5 -139 o37.5 -112
Sun (10/22) @ 4:26pm ET LA Chargers u50.5 -110 u50.5 -115 u54.5 +100 u48.5 -110 u48.5 -110 u47.5 -105 u47.5 0
KC Chiefs o50.5 -110 o50.5 -115 o54.5 -130 o48.5 -110 o48.5 -110 o47.5 -115 o47.5 0
Sun (10/22) @ 8:23pm ET MIA Dolphins o52.5 -110 o50.5 -141 o50.5 -120 o51.5 -110 o51 0
PHI Eagles u52.5 -110 u50.5 +110 u50.5 -110 u51.5 -118 u51 0
Mon (10/23) @ 8:16pm ET SF 49ers u44.5 -110 u39.5 -196 u39.5 -10000 u44 -110 u44.0 -108 u47.5 +100 u39.5 -294
MIN Vikings o44.5 -110 o39.5 +150 o39.5 +3300 o44 -110 o44.0 -114 o47.5 -130 o39.5 +220

Here’s a game-by-game look at the Week 7 slate with opening lines from DraftKings as of Friday, Oct. 21.

Chiefs (-2, 49) at 49ers

Kansas City Chiefs quarterback Patrick Mahomes (AP Photo/Michael Conroy)

San Francisco’s 2-0 record at home came after solid wins over the Seahawks (27-7)  and Rams (24-9) earlier this season. Dating back to last season, the 49ers are 5-0 ATS in their last five home games. Expect KC to provide a stiff test against San Francisco’s banged-up defensive unit on Sunday, though.

Browns at Ravens (-6.5, 46)

Slight movement toward the home favorite here after Baltimore opened -6. The Ravens and Browns split the season series last year with both teams winning at home. But Baltimore has covered in its last three games against Cleveland.

Also read: Risers and fallers in Super Bowl 57 futures odds

Giants at Jaguars (-3, 43)

The Jags opened -2 but they’re now laying a full FG to New York. Bettors are showing little respect for the 5-1 Giants against a Jacksonville team that’s 2-4.

Bucs (-13, 39.5) at Panthers

This line moved in a major way after the Panthers traded Christian McCaffrey to the 49ers on Thursday. The line had already crept to -11 before the deal was done, but the Bucs were laying -13 after news of the trade broke Friday morning.

Falcons at Bengals (-6.5, 47)

The only movement here involved a two-point rise in the total after an opener of 45. Tip of the cap to the Falcons after they ran their ATS record to 6-0 following a 28-14 win over San Francisco.

NFL prop betting: Use BetMGM Promo Code ‘TODAY’ & Get $1,000 Risk Free Bet

Lions at Cowboys (-6.5, 49)

Dallas has played to the Under in its last five games, but starting QB Dak Prescott returns for the first time since the season opener to face the Lions. Given Detroit allows the most points per game (34), expect the Cowboys to explode with Dak back. He led the Cowboys to a league-high 31.2 points per game last season.

Colts at Titans (-2.5, 42)

Tennessee has owned Indianapolis as of late. The Titans have now won four straight games against the Colts including a 24-17 road victory at Indy on Oct. 2.

Packers (-4.5, 41.5) at Commanders

The Commanders will be without starting QB Carson Wentz (finger), but Washington money dropped this from an opener of Green Bay -5.5.

Seahawks at Chargers (-5, 50.5)

Bettors are believing in the Geno Smith-led Seahawks, as Seattle support shaved the opener of Chargers -7 by a full two points. LA won at home but failed to cover against Denver, 19-16, on Monday Night Football.

Bears at Patriots (-8, 40)

The Patriots opened at -7.5 and they should be able to pick their score here. The problem for Chicago is the Bears can’t score. Only Denver scores less than Chicago, which ranks 31st in the NFL with 15.5 points per game.

Bet NFL Futures at FanDuel: $1,000 No Sweat First Bet

The Rest of NFL Week 7 Games

Texans at Raiders (-7, 46)

Four of the last five games between these two teams have gone Over. Perhaps that helps explain why bettors hammered the total up from an opener of 42.

Jets at Broncos (-1, 38.5)

Russell Wilson was limited in practice this week, and Brett Rypien shared QB reps. That uncertainty made the Jets an even more attractive play after Denver opened at -3.5. The Jets are now 5-1 ATS in their last six road games after last Sunday’s outright win at Green Bay.

Steelers at Dolphins (-7, 45.5)

Miami QB Tua Tagovailoa will start against the Steelers after clearing concussion protocol. The Dolphins took some money here after opening -6.

About the Author
Kris Johnson

Kris Johnson

Senior Writer
Kris Johnson is a senior writer at Gaming Today with more than 15 years of experience as a sports journalist. Johnson's work has appeared in Sports Business Daily, Sports Business Journal, NASCAR Illustrated, and other publications. He also authored a sports betting novel titled The Endgame.

Get connected with us on Social Media