Sunday’s Super Bowl 54 rematch between the Kansas City Chiefs and San Francisco 49ers got a little more interesting after the 49ers traded for Carolina RB Christian McCaffrey on Thursday.
DraftKings opened with Kansas City -2.5 earlier this week, but the line had dropped to -2 as of Friday morning. San Francisco remains a short home dog, and the 49ers are 2-0 ATS at Levi’s Stadium.
The following teams have a bye in Week 7: Bills, Rams, Vikings, and Eagles.
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Here’s a game-by-game look at the Week 7 slate with opening lines from DraftKings as of Friday, Oct. 21.
Chiefs (-2, 49) at 49ers

San Francisco’s 2-0 record at home came after solid wins over the Seahawks (27-7) and Rams (24-9) earlier this season. Dating back to last season, the 49ers are 5-0 ATS in their last five home games. Expect KC to provide a stiff test against San Francisco’s banged-up defensive unit on Sunday, though.
Browns at Ravens (-6.5, 46)
Slight movement toward the home favorite here after Baltimore opened -6. The Ravens and Browns split the season series last year with both teams winning at home. But Baltimore has covered in its last three games against Cleveland.
Also read: Risers and fallers in Super Bowl 57 futures odds
Giants at Jaguars (-3, 43)
The Jags opened -2 but they’re now laying a full FG to New York. Bettors are showing little respect for the 5-1 Giants against a Jacksonville team that’s 2-4.
Bucs (-13, 39.5) at Panthers
This line moved in a major way after the Panthers traded Christian McCaffrey to the 49ers on Thursday. The line had already crept to -11 before the deal was done, but the Bucs were laying -13 after news of the trade broke Friday morning.
Falcons at Bengals (-6.5, 47)
The only movement here involved a two-point rise in the total after an opener of 45. Tip of the cap to the Falcons after they ran their ATS record to 6-0 following a 28-14 win over San Francisco.
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Lions at Cowboys (-6.5, 49)
Dallas has played to the Under in its last five games, but starting QB Dak Prescott returns for the first time since the season opener to face the Lions. Given Detroit allows the most points per game (34), expect the Cowboys to explode with Dak back. He led the Cowboys to a league-high 31.2 points per game last season.
Colts at Titans (-2.5, 42)
Tennessee has owned Indianapolis as of late. The Titans have now won four straight games against the Colts including a 24-17 road victory at Indy on Oct. 2.
Packers (-4.5, 41.5) at Commanders
The Commanders will be without starting QB Carson Wentz (finger), but Washington money dropped this from an opener of Green Bay -5.5.
Seahawks at Chargers (-5, 50.5)
Bettors are believing in the Geno Smith-led Seahawks, as Seattle support shaved the opener of Chargers -7 by a full two points. LA won at home but failed to cover against Denver, 19-16, on Monday Night Football.
Bears at Patriots (-8, 40)
The Patriots opened at -7.5 and they should be able to pick their score here. The problem for Chicago is the Bears can’t score. Only Denver scores less than Chicago, which ranks 31st in the NFL with 15.5 points per game.
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The Rest of NFL Week 7 Games
Texans at Raiders (-7, 46)
Four of the last five games between these two teams have gone Over. Perhaps that helps explain why bettors hammered the total up from an opener of 42.
Jets at Broncos (-1, 38.5)
Russell Wilson was limited in practice this week, and Brett Rypien shared QB reps. That uncertainty made the Jets an even more attractive play after Denver opened at -3.5. The Jets are now 5-1 ATS in their last six road games after last Sunday’s outright win at Green Bay.
Steelers at Dolphins (-7, 45.5)
Miami QB Tua Tagovailoa will start against the Steelers after clearing concussion protocol. The Dolphins took some money here after opening -6.