North Carolina and Clemson head into Saturday’s ACC Championship game licking their wounds after losses to in-state rivals last weekend.
North Carolina vs. Clemson odds are now available on top sports betting apps including DraftKings.
UNC is coming off a 30-27 OT loss to NC State — its second loss in as many weeks after falling to Georgia Tech, 21-17. Meanwhile, South Carolina defeated Clemson, 31-30.
ABC will have live coverage of the ACC Championship game from Bank of America Stadium in Charlotte starting at 8 p.m. ET on Saturday. Here is a look at North Carolina vs. Clemson betting odds and a prediction.
North Carolina vs. Clemson Betting Lines: Point Spread, Total, Moneyline
Here are live odds from across the sports betting industry as the Tar Heels and Tigers square off for ACC supremacy.
No. 24 North Carolina Tar Heels (9-3 Overall, 6-5-1 Against the Spread)
UNC has one of the most dynamic offenses in the country. QB Drake Maye was on his way to New York City as a Heisman Trophy candidate before the Tar Heels dropped their last two games of the regular season. Both DraftKings and FanDuel had Maye off the Heisman betting board as of this writing.

It’s still been a remarkable season for Maye, who has thrown for 3,847 yards and 35 TDs (tied for fourth nationally). WR Josh Downs is UNC’s top playmaker. Despite missing some games early in the season due to a knee injury, Downs led the Tar Heels in receiving yards (929) and TD catches (11).
UNC’s offense is among the most productive in the nation with an average of 480.9 yards and 37.1 points per game. The Tar Heels topped the ACC in both categories. Conversely, UNC has the worst defense in the conference with 442.7 yards and 30.3 points allowed per game.
Also read: Heisman Trophy 2022 odds
No. 10 Clemson Tigers (10-2 Overall, 7-5 ATS)
Clemson stubbed its toe with two losses in November to Notre Dame and South Carolina, respectively. Last week’s loss as a 14-point favorite to the Gamecocks was particularly painful as it killed any chance of Clemson advancing to the College Football Playoff.
Will Shipley is Clemson’s bellcow at RB. Shipley has 1,092 rushing yards and 14 TDs on the ground. QB DJ Uiagalelei is the second-leading rusher on the team with 545 yards. Uiagalelei struggled late in the season and gave way to freshman phenom Cade Klubnik in a 27-21 win against Syracuse.
Uiagalelei threw for just 99 yards with one TD and a pick in the loss to South Carolina. He added another TD on the ground. Head coach Dabo Swinney will reportedly stick with Uiagalelei to start against UNC.
Clemson will field a much better defense in this title tilt. The Tigers ranked fourth in the ACC, yielding just 20.9 points per game. DE Myles Murphy leads a solid front four for Clemson with a team-high 6.5 sacks. LB Jeremiah Trotter Jr. leads the Tigers with 71 total tackles.
North Carolina vs. Clemson Betting Recommendation & Pick
Both of these teams ruined any chance of sneaking into the College Football Playoff even if they win on Saturday. North Carolina has dropped two straight games, but its high-powered offense should give the Tar Heels a chance to win outright.
One key to this game will be Maye’s ability to run and Clemson’s ability to stop him (or not) when plays break down. In addition to his gaudy passing stats, Maye’s got 691 rushing yards and six TDs on the ground this season.
Our Pick: North Carolina +7.5
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