Rams At 49ers Odds, Betting Analysis, Pick: San Francisco Underdog To Earn Rare Home Win On MNF

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The line in the NFL’s Week 10 Monday Night Football matchup featuring the NFC West rivals Rams and 49ers was bet up from an opener of L.A. -3 and ranged between 3.5 and 4.5 during early wagering.

LA Rams vs SF 49ers Odds NFL Odds

NFL · Mon (11/15) @ 8:15pm ET

LA Rams at SF 49ers
Levi's Stadium, Santa Clara, California

For new DraftKings customers: Make $1 moneyline bet, earn $100 in free wagers

Rams (7-2, 4-5 ATS) at 49ers (3-5, 2-6 ATS)

DraftKings line: Rams -3.5 (49)

The skinny: The Rams, tied with Green Bay with the second-best record in the NFC at the midpoint of the season, look to keep pace with division front-runner Arizona in hopes of getting that first-round bye.

Facts: Rams QB Matt Stafford (questionable, ankle), the league’s second-rated QB, entered last week’s home game against Tennessee with only four INTs in eight games, but threw two in a matter of 20 seconds — one a pick-six, another that resulted in a return to the L.A. 2 — that played a key role in the Ram’ 28-16 defeat.

The Rams gave up only 194 yards of total offense to a Titans team playing without rushing leader Derrick Henry (IR, foot), the only time this season a team won despite gaining fewer than 200 yards. In Week 8 last season, much the same thing happened to the Rams, who were 28-17 losers to Miami, even though the Dolphins gained only 145 yards.

San Francisco had high hopes of returning to relevance in the division last week on the heels of its 33-22 road win at Chicago. Instead, the 49ers were 31-17 losers as 5.5-point home favorites against an Arizona team minus QB Kyler Murray, WR DeAndre Hopkins, and defensive standout J.J. Watt, and going with backup QB Colt McCoy.

Analysis: If the Rams hold the 49ers to fewer than 200 yards of offense, this should be a solid victory for L.A. in San Francisco, where the 49ers have lost all but one of their past nine games.

L.A.’s Cooper Kupp, the league’s receiving leader in catches and yards, should thrive. And look out if the Rams get WR Odell Beckham Jr. into the lineup after picking him up off waivers.

Playing Monday night and getting extra rest can’t help but benefit Stafford’s ankle and back issues. It’s uncertain whether newly acquired Von Miller (ankle) will be active or given another week’s rest before the team’s Week 11 bye that precedes a crucial game at Green Bay.

But L.A. has enough of a pass rush to cause San Fran QB Jimmy Garoppolo to have his usual assortment of overthrows and sacks. He went down five times last week.

Rams at 49ers Pick

Rams 29, 49ers 14

Last week: 5-9 ATS, 8-6 SU
Season total: 67-66-3 (.504) ATS; 85-51 (.625) SU

About the Author

Bob Christ

Bob Christ, based in New Mexico, has been a gaming writer (primarily the NFL) for almost four decades, with his work appearing in publications/websites across North America. He's a big fan of the Arkansas Razorbacks, Philadelphia's Eagles and Phillies, and inexplicably the NHL's Winnipeg Jets.

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