Real Madrid vs. Liverpool Odds, Props & Prediction: Reds Need Champions League Miracle

Real Madrid and Liverpool meet again on Wednesday after Los Blancos won Leg 1 in a stunning 5-2 comeback after falling into a 2-0 hole.

In Gaming Today’s analysis of the Real Madrid vs. Liverpool odds, props, and predictions for the Champions League Round of 16 Leg 2 clash, we break down whether Real Madrid will be able to protect their massive lead at home against Jurgen Klopp’s side.

On Feb. 21 at Anfield, Liverpool led 2-0 after 15 minutes thanks to goals by Darwin Nunez and Mohamed Salah. But Real Madrid dominated the rest of that match, tying the score before halftime, then piling on three quick goals after the break for a 5-2 lead in front of a stunned home crowd.

Real Madrid vs. Liverpool Odds: Moneyline, Total, To Advance

Here are the betting lines from top US sportsbooks for Tuesday’s Champions League match between Real Madrid and Liverpool. The odds are likely to change between now and kickoff, and it’s always advised to weigh the options at various sports betting apps to find the best sportsbook bonuses and prices for your bets.

These odds reflect the prices for both sides on the three-way line, where a bet on either team is a loss in the event of a draw. DraftKings lists the draw at +290, while FanDuel offers +300, and Caesars lists it at +270.

Bookmakers also offer the option to bet on which team will advance. DraftKings lists Real Madrid at -6000 and Liverpool at +1400 to reach the quarterfinals.

Real Madrid Roster, Injuries, and Betting News

Real Madrid are in danger of losing their shot at a La Liga title before the calendar turns to April, but they’re still one of the favorites to win the Champions League. With their work in the round of 16 99% done, this team led by veteran stars Luka Modric, Toni Kroos, and Karim Benzema will be a tough out for whoever they draw in the next round, assuming their three-goal cushion holds up.

Injuries

Real Madrid have a couple key players on the back line in left back Ferland Mendy and David Alaba, who are either out or less than 100%. The former has been cleared to return from a lengthy absence, but seems unlikely to start, while Los Blancos confirmed they will be without David Alaba.

“Worst case,” though, a foursome of Nacho, Eder Militao, Antonio Rudiger, and Dani Carvajal are solid enough to have Madridistas confident they can keep Wednesday’s match from getting interesting.

Star striker Benzema missed his team’s last game over the weekend but is expected to start against Liverpool.

Liverpool Roster, Injuries, and Betting News

Liverpool have reminded us a few times in recent weeks that they’re still the team that won the Champions League in 2019 (and the Premier League in 2020) and reached last year’s Champions League final.

While going up 2-0 against Real Madrid in Leg 1 and blowing out Manchester United 7-0 on March 5 turned heads, the rest of the Leg 1 match-up against RM and the most recent showing — a 1-0 loss to Bournemouth — showed that this team has some massive holes, particularly in the midfield.

The likes of goalkeeper Alisson, center back Virgil van Dijk, and winger Mo Salah remain among the best players in the world, but the squad as a whole is flawed, as their Premier League record of 12-6-8 indicates.

Injuries

Injuries have played a big part in Liverpool’s struggles this season. While they have had a few key players return in recent weeks, they’ll likely be missing midfielders Jordan Henderson, Stefan Bajcetic, and Thiago Alcantara on Wednesday.

The good news for the Reds is that winger Luis Diaz and center back Joe Gomez could return from their injuries, as they participated in training early this week.

Real Madrid vs. Liverpool Props

Below is a sampling of props for Real Madrid vs. Liverpool.

Anytime Goalscorer (FanDuel):

• Karim Benzema: +115
• Rodrygo: +170
• Mohamed Salah: +175
• Darwin Nunez: +185
• Vinicius: +195

Correct Score (FanDuel):

• Real Madrid 1-0: +1100
• Real Madrid 2-0: +1300
• Real Madrid 2-1: +800
• Liverpool 1-0: +1300
• Liverpool 2-0: +1600
• Liverpool 2-1: +950
• 0-0: +1800
• 1-1: +700

Total Goal Props (DraftKings):

• Over 0.5 goals -6000, Under 0.5 goals: +1400
• Over 1.5 goals -650, Under 1.5 goals: +425
• Over 2.5 goals -190, Under 2.5 goals: +150
• Over 3.5 goals +135, Under 3.5 goals: -165

Real Madrid vs. Liverpool Broadcast Info: Where to Watch

• Date/Time: Wednesday, March 15, 4 p.m. ET
• Location: Santiago Bernabeu

Watch this match at one of the following:

• Paramount+
• ViX+
• Univision
• TUDN
• fubo TV
• DirecTV Stream

Real Madrid vs. Liverpool Prediction: Real Madrid 1, Liverpool 1

It’s hard to handicap or predict a game when one team enters the match with a three-goal lead. Recent Champions League history, especially involving Real Madrid, has shown us that multi-goal gaps can be closed in no time under the right circumstances. But it’s hard to imagine a team managed by Carlo Ancelotti — and boasting as much experience as RM — capitulating at home.

Liverpool will come out on the front foot. And it shouldn’t shock anyone if they score first, lead at halftime and/or win Leg 2.

They’re down too much, though — and the difference between Anfield in 2019 vs. Barcelona and the Santiago Bernabeu in 2023 vs. Real Madrid is too great — for them to pull off another Champions League miracle this time.

Here are a few bets available at DraftKings that are worth checking out:

• First Goal — Liverpool (+100)
• Under 2.5 Total Goals (+150)

Also read: Premier League futures | 2026 World Cup odds