Share 
Lamar Jackson has only an outside chance to play Sunday night, and the Ravens were 3.5-point favourites at the Falcons before that news broke. That line is the one to watch in NFL Week 5, which also brings the first byes and a 9:30 a.m. ET kickoff in London.
Spend $5+ Get $150 in Bonus Bets Over 14 Days
Plus Get up to $1,000 Deposit Bonus
Bet on All Your Favorite Sports With America's Top-Rated Sportsbook
Spend $5+ Get $150 in Bonus Bets Over 14 Days
Plus Get up to $1,000 Deposit Bonus
Bet on All Your Favorite Sports With America's Top-Rated Sportsbook
Up to $500 in Bet Credits
ONLY 1x Play Through!
Stream Pro Sports on Mobile or Desktop
Up to $500 in Bet Credits
ONLY 1x Play Through!
Stream Pro Sports on Mobile or Desktop
10x No Sweat Bets up to $50 Over Next Ten Days
Game Lines, Prop Bets & Parlays for Days
10x No Sweat Bets up to $50 Over Next Ten Days
Game Lines, Prop Bets & Parlays for Days
Dallas is the only double-digit favourite, laying about 10 to a winless Tampa Bay on Thursday night. Here are the current NFL odds for every game, the lines that moved, and the three injury calls that could move them again.
Get $250 in Bonus Bets When You Wager $5 for 5 Days ($50 Bonus Bets Per Day)
Available on Desktop, Android & iOS
Easy Deposits, Fast Withdrawals
Get $250 in Bonus Bets When You Wager $5 for 5 Days ($50 Bonus Bets Per Day)
Available on Desktop, Android & iOS
Easy Deposits, Fast Withdrawals
Bet $10 Get $200 in Bonus Bets Win or Lose
30% Extra on Same Game Parlay Profit
T&Cs Apply. Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET (AZ, CO, IL, IN, KS, KY, LA, MD, MI, MO, NC, NJ, OH, PA, TN, VA, WV) or 1-800-BETS OFF (IA). 21+ only. Please gamble responsibly. Must be present in AZ/CO/IA/IL/IN/KS/KY/LA(select parishes) /MD/MI/MO/NC/NJ/OH/PA/TN/VA/WV.
Bet $10 Get $200 in Bonus Bets Win or Lose
30% Extra on Same Game Parlay Profit
T&Cs Apply. Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET (AZ, CO, IL, IN, KS, KY, LA, MD, MI, MO, NC, NJ, OH, PA, TN, VA, WV) or 1-800-BETS OFF (IA). 21+ only. Please gamble responsibly. Must be present in AZ/CO/IA/IL/IN/KS/KY/LA(select parishes) /MD/MI/MO/NC/NJ/OH/PA/TN/VA/WV.
Up to $1,500 in Bonus Bets if Your First Bet Doesn't Win*
*Bonus Bets Expire in 7 Days. One New Customer Offer Only. Add’l terms. 21+. Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET
Up to $1,500 in Bonus Bets if Your First Bet Doesn't Win*
*Bonus Bets Expire in 7 Days. One New Customer Offer Only. Add’l terms. 21+. Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET
Odds were checked on 8 October, before Thursday’s injury news, and they move constantly. Confirm the current number at your sportsbook before acting on anything here.
NFL Week 5 Odds: Full Board
| Matchup | Spread | Moneyline | Total | When |
|---|---|---|---|---|
| Buccaneers at Cowboys | DAL -10 | DAL -500, TB +380 | 47.5 | Thu 8:15 p.m. ET, Prime Video |
| Eagles vs Jaguars (London) | JAX -5.5 | JAX -245, PHI +200 | 42.5 | Sun 9:30 a.m. ET, NFL Network |
| Bears at Packers | CHI -3 | CHI -166, GB +140 | 44.5 | Sun |
| Bengals at Dolphins | CIN -7.5 | CIN -345, MIA +275 | 42.5 | Sun |
| Browns at Jets | NYJ -1.5 | NYJ -120, CLE +100 | 40.5 | Sun |
| Texans at Titans | HOU -7 | HOU -340, TEN +290 | 39.5 | Sun |
| Colts at Steelers | PIT -2.5 | PIT -135, IND +114 | 44.5 | Sun |
| Raiders at Patriots | NE -3.5 | NE -190, LV +160 | 45.5 | Sun |
| Giants at Commanders | WAS -3 | WAS -175, NYG +145 | 44.5 | Sun |
| Vikings at Saints | MIN -1.5 | MIN -125, NO +105 | 41.5 | Sun |
| Broncos at Chargers | DEN -3.5 | DEN -185, LAC +155 | 42.5 | Sun 4:05 p.m. ET |
| Lions at Cardinals | DET -4.5 | DET -220, ARI +180 | 53.5 | Sun 4:25 p.m. ET |
| 49ers at Seahawks | SEA -2.5 | SEA -148, SF +124 | 47.5 | Sun 4:25 p.m. ET |
| Ravens at Falcons | BAL -3.5 | BAL -200, ATL +165 | 46.5 | Sun 8:20 p.m. ET, NBC |
| Bills at Rams | LAR -2.5 | LAR -142 | 53.5 | Mon 8:15 p.m. ET, ESPN |
Spreads and totals are the 5 October consensus. Some books differ by a point or more: Dallas ranges from -8.5 to -10, and Jacksonville from -4.5 to -6.5. The Chiefs and Panthers are on bye, so Week 5 has 15 games.
The Line Everyone Is Waiting On: Ravens at Falcons
Ravens -3.5 at Falcons, total 46.5. The number has barely moved since it opened, and that is about to end.
Jackson left Sunday’s 24-18 win over Tennessee with a sprained ankle. NFL Network reports he has only an outside chance to play, and that he could miss several games. Tyler Huntley would start in his place.
Atlanta also scored 45 against New Orleans on Monday night. A Ravens spread of -3.5 assumes Jackson plays and the Falcons are average. Neither may be true. Expect this line to move all week, and wait for the Friday injury report before taking it.
Three Spreads That Are Provisional
- Giants at Commanders, WAS -3. Jayden Daniels, out with an elbow dislocation, is hoped to return. Backup Marcus Mariota left Sunday’s loss with a knee injury, so rookie Athan Kaliakmanis is next in line.
- Bengals at Dolphins, CIN -7.5. The line fell from -8.5 and the total from 46.5 to 42.5 after Ja’Marr Chase entered the concussion protocol and Tee Higgins hurt his adductor.
- Eagles at Jaguars, JAX -5.5. Saquon Barkley is week-to-week with a hamstring injury. The spread opened at 3 and has climbed.
Our Week 5 news roundup covers each of these in detail.
What Moved Since the Opener
| Game | Opened | Now | Why |
|---|---|---|---|
| Eagles vs Jaguars | JAX -3 | JAX -4.5 or more | Barkley’s hamstring and an 0-4 Eagles record against the spread |
| Bengals at Dolphins | CIN -8.5 | CIN -7.5 | Chase and Higgins injured |
| Bears at Packers | CHI -1.5 | CHI -2.5 to -3 | Chicago 3-1 against the spread |
| Vikings at Saints | MIN -2.5 | MIN -1.5 | Money on New Orleans |
| Bills at Rams | LAR -3 | LAR -2.5 | Buffalo’s loss to New England |
| Buccaneers at Cowboys | DAL -9.5 | DAL -10 | Backup quarterback for Tampa Bay |
Opening lines are DraftKings. Reasons are the market’s likely drivers, not confirmed by the books.
The London Game: A 9:30 A.M. Kickoff
Eagles vs Jaguars, JAX -5.5, total 42.5. This is the second London game in a row, at Tottenham Hotspur Stadium on NFL Network. Jacksonville is the designated home team.
The Jaguars are 3-1 straight up and against the spread, with an average winning margin of 12.8 points, second best in the league. Philadelphia is 0-4 against the spread and led the Rams 20-10 at halftime last week before being shut out in the second half. The inactive list for this game arrives around 8:00 a.m. ET on Sunday.
Totals: The High and the Low
- Highest: Lions at Cardinals, 53.5. Tied with Bills at Rams on Monday night at 53.5.
- Lowest: Texans at Titans, 39.5. Followed by Browns at Jets at 40.5 and Vikings at Saints at 41.5.
The Texans and Titans are both 0-4. Five teams are winless this week: the Dolphins, Buccaneers, Titans, Texans and Chargers. Several of them play each other or another struggling team, which is why so many totals sit in the low 40s.
Who Is Covering and Who Is Not
| Against the spread | Teams |
|---|---|
| Best (3-1) | Bears, Browns, Jaguars, Cowboys, Bills, 49ers |
| Worst (0-4 or 0-3-1) | Buccaneers, Eagles, Texans, Chargers |
| Also struggling | Ravens (1-3), Packers (1-3) |
Records are through NFL Week 4 and come from CBS Sports and Sports Betting Dime. They will have changed by Sunday.
What Week 4 Told the Market
- Underdogs won seven games outright. The Browns, Giants, Cowboys, Jaguars, Patriots, Panthers and Falcons all won as underdogs.
- The biggest favourites won but did not cover. Baltimore, an 11.5-point favourite, beat Tennessee 24-18. Minnesota, a 10.5-point favourite, beat Miami 15-10.
- Favourites of a field goal or more were not safe. Buffalo lost 29-26 to New England as a 6.5-point favourite, and Detroit lost 32-26 at Carolina as a 3.5-point road favourite.
How to Read the Week 5 Board
- Treat Ravens at Falcons as unpriced. Wait for Friday’s report.
- Respect the key numbers. Pittsburgh at -2.5 and Seattle at -2.5 sit just under 3. A three-point win pushes at -3.
- Check the rest. Indianapolis flies back from London to play Pittsburgh, who played last Thursday and had extra days to prepare. The Browns also played Thursday and visit a Jets team that played Sunday.
- Shop the number. Half a point across books matters most at 3 and 7.
New to any of this? Our guide to reading NFL odds explains spreads, totals and moneylines in plain English. For our selections, see our Week 5 best bets, and for this week’s sportsbook offers see our NFL betting promos this week.
Frequently Asked Questions
What is the biggest spread in NFL Week 5?
Dallas at about -10 against Tampa Bay on Thursday night. It is the only double-digit spread on the board.
What is the highest total in Week 5?
Lions at Cardinals and Bills at Rams, both at 53.5. The lowest is Texans at Titans at 39.5.
Is Lamar Jackson playing in Week 5?
Not confirmed. He sprained his ankle in Week 4 and has only an outside chance to play, according to NFL Network. Tyler Huntley would start if he cannot.
What time is the NFL London game in Week 5?
Eagles vs Jaguars kicks off at 9:30 a.m. ET on Sunday 11 October at Tottenham Hotspur Stadium and airs on NFL Network. Jacksonville is about a 5-point favourite.
Which teams are on bye in Week 5?
The Kansas City Chiefs and the Carolina Panthers. That leaves 15 games.
Which game opens Week 5?
Buccaneers at Cowboys on Thursday night, 8:15 p.m. ET on Prime Video. Dallas is about a 10-point favourite and the total is 47.5.
Odds are subject to change and were accurate at the time of writing. Always confirm the current line at your sportsbook before placing a wager. You must be 21 or older and physically located in a state where sports betting is legal. Nothing here is a guarantee of any outcome. Please gamble responsibly. If gambling stops being fun, call 1-800-GAMBLER for confidential support.
